| Sequence 1: | NP_000416.1 | Gene: | L1CAM / 3897 | HGNCID: | 6470 | Length: | 1257 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001245581.1 | Gene: | Nrg / 31792 | FlyBaseID: | FBgn0264975 | Length: | 1309 | Species: | Drosophila melanogaster |
| Alignment Length: | 1270 | Identity: | 365/1270 - (28%) |
|---|---|---|---|
| Similarity: | 596/1270 - (46%) | Gaps: | 135/1270 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Human 12 LLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPT--------DDISLKCEASGKPEVQFR 68
Human 69 WTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAE 133
Human 134 GAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKIL--HIK--QDERVTMGQNGNLY 194
Human 195 FANVLTSDNHSD--YICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN---SSSHL 252
Human 253 VALQGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAEN 316
Human 317 SLGSAR-HAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ 380
Human 381 KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV-------VQLPAKILTADNQTYMA 438
Human 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQ 503
Human 504 NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDK 568
Human 569 YFIE--DGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQS-Q 630
Human 631 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKW-YSLGKVPGNQTSTTLKLSPYVHYTFRVTAINK 694
Human 695 YGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGT 759
Human 760 RGPWQEQIVSD---PFLVVSNTSTFVPYEIKVQAVNSQGK-GPEPQVTIGYSGEDYPQAIP-ELE 819
Human 820 GIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSG 884
Human 885 LRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVL 948
Human 949 TGYVLSYHPLDE---GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGG 1010
Human 1011 TMALSGISDFGNISATAGENYS-------------VVSWVPK-EGQCNFRFHILFKALGEEKGGA 1061
Human 1062 SLSPQYVSYNQSSYTQWD----LQPDTDYEIHLFK-ERMFRHQMA---VKTNGT-GRVRLPPAGF 1117
Human 1118 ATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDE-TFGEYRSLES 1181
Human 1182 DNE----EKAFGSSQPSLNGDIKPLGSDDSLADYG 1212 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| L1CAM | NP_000416.1 | IG_like | 42..125 | CDD:214653 | 24/90 (27%) |
| Ig6_L1-CAM_like | 53..130 | CDD:143210 | 24/76 (32%) | ||
| Ig | 134..228 | CDD:299845 | 31/101 (31%) | ||
| IG_like | 249..329 | CDD:214653 | 22/81 (27%) | ||
| Ig3_L1-CAM_like | 260..330 | CDD:143208 | 19/71 (27%) | ||
| IG_like | 339..421 | CDD:214653 | 19/81 (23%) | ||
| Ig4_L1-CAM_like | 347..422 | CDD:143275 | 19/81 (23%) | ||
| IG_like | 434..514 | CDD:214653 | 23/79 (29%) | ||
| Ig | 441..514 | CDD:299845 | 23/72 (32%) | ||
| I-set | 519..608 | CDD:254352 | 30/90 (33%) | ||
| IGc2 | 532..594 | CDD:197706 | 19/63 (30%) | ||
| Cell attachment site. /evidence=ECO:0000255 | 554..556 | 0/1 (0%) | |||
| FN3 | 612..709 | CDD:238020 | 31/98 (32%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 698..725 | 10/26 (38%) | |||
| fn3 | 718..799 | CDD:278470 | 29/84 (35%) | ||
| fn3 | 824..907 | CDD:278470 | 24/82 (29%) | ||
| FN3 | 918..1003 | CDD:238020 | 26/87 (30%) | ||
| fn3 | 1021..1109 | CDD:278470 | 22/110 (20%) | ||
| Bravo_FIGEY | 1144..1233 | CDD:290593 | 23/74 (31%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1176..1207 | 6/34 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1226..1257 | ||||
| Nrg | NP_001245581.1 | Ig | 55..128 | CDD:299845 | 24/77 (31%) |
| IG_like | 57..127 | CDD:214653 | 24/74 (32%) | ||
| Ig | 135..214 | CDD:299845 | 26/78 (33%) | ||
| IG_like | 141..216 | CDD:214653 | 26/74 (35%) | ||
| ig | 251..332 | CDD:278476 | 23/80 (29%) | ||
| I-set | 339..427 | CDD:254352 | 21/87 (24%) | ||
| Ig | 354..427 | CDD:299845 | 18/72 (25%) | ||
| I-set | 432..517 | CDD:254352 | 27/94 (29%) | ||
| Ig | 446..517 | CDD:299845 | 23/72 (32%) | ||
| I-set | 522..611 | CDD:254352 | 30/90 (33%) | ||
| ig | 525..609 | CDD:278476 | 27/85 (32%) | ||
| FN3 | 613..707 | CDD:238020 | 31/99 (31%) | ||
| FN3 | 716..807 | CDD:238020 | 30/90 (33%) | ||
| fn3 | 817..905 | CDD:278470 | 26/93 (28%) | ||
| FN3 | 917..1004 | CDD:238020 | 26/86 (30%) | ||
| FN3 | 1041..1111 | CDD:238020 | 16/77 (21%) | ||
| Bravo_FIGEY | 1155..>1221 | CDD:290593 | 23/74 (31%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 66 | 1.000 | Domainoid score | I9917 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3513 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 603 | 1.000 | Inparanoid score | I950 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG47974 | |
| OrthoDB | 1 | 1.010 | - | - | D208655at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000777 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40969 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101169 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X532 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.740 | |||||