Protein Alignment ZC3H3 and zc3h3

DIOPT Version :10

• Sequence 1: NP_648230.1
• Gene: ZC3H3 / 38968
• FlyBaseID: FBgn0035900
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_689680.3
• Gene: zc3h3 / 561182
• ZFINID: ZDB-GENE-030131-9399
• Length: 929
• Species: Danio rerio
• Alignment Length: 740
• Identity: 189/740 - (25%)
• Similarity: 277/740 - (37%)
• Gaps: 229/740 - (30%)

  Fly     3 PHISADEAQPSMSRKVYINPNFQLQGQTAHQLPFQVPFQAFQAPLQPQPAIHINPHFLNRQRAMY 67
            ||:...    |.|.:..:.|:.:....||.... .:..||..:|.:||..:.     ..:..|..
Zfish   221 PHLPPS----SSSNRTVVIPSAKKDSTTASSAS-NLQSQATVSPAKPQVKLD-----STQTHAAS 275

  Fly    68 DQYQREQQEQLMMQQVSASHYRLDPTIHLLATPPP-----PPAKII----SKVSTCLVRKP---- 119
            ..::|.|...:..|:          |:::.:||.|     .|..|.    |..|..:.|||
Zfish   276 PCHKRSQFTWVKSQE----------TVNINSTPKPLTSGSSPGMIFTRRASSSSKRVSRKPNNSP 330

  Fly   120 ---------------SVVASG---PAVKL--------AASVPVPT-------VSSLVQPPLVSIS 151
                           |:..:|   |:|||        :...||.|       :....:...|:::
Zfish   331 GAPKTSKYTWVSSSCSLSTAGKANPSVKLPRKPLSPKSLKAPVRTFQGGMEGIKKEKKYTTVTVT 395

  Fly   152 KRKIVRQGAL-------------KAA--------------------------------------- 164
            ..|..|.||:             |||
Zfish   396 PLKKSRAGAVTTSHASHTSRYRWKAAGQNANASTSSSASRTTHKSTVYRWTANNNGQKGEKGSTL 460

  Fly   165 ----PAVAALHPPPPAKRTRYKLV-RSISLTCTPLVKKRRP-LREFVGQYAL-RRTN-------- 214
                ||.|||.......|:|.|:: ||.|..|  |.::..| ::....:|:| |||:
Zfish   461 SPNIPATAALSVGAFKLRSRTKIIRRSPSNPC--LERRHSPNVQTLKSRYSLWRRTHTQVKSPTS 523

  Fly   215 --EAQPN----------RKLSSKPQALKLGVNKS-LSMVSIHGVMYKKISKNKITKLDA------ 260
              .|||.          |:||.  .:..||.::| .|..|:......::.|.:. |:|.
Zfish   524 IKRAQPKVLVSFGRHKLRRLSL--TSTSLGTSRSGPSSSSVRSPASHRVIKTRY-KIDTRRAHAI 585

  Fly   261 ----SSSARVAKSESPRTL----QRTLSGRTLFVSGNKFILDPSGCRLTRVSTSSTGATQSSVNR 317
                :.|.||.:..|.|.|    .||.|.|.......::|    |..|.|||.:....||::
Zfish   586 HHNPALSYRVKRVHSARALLQNRMRTTSERQWRGRSMRWI----GGELYRVSANKLSRTQTT--- 643

  Fly   318 SILRRIDIGGLTYVASP-KALNVFVRTSNHVSRAHLI-----TAKQRSLTLL---NKSLVKTNVP 373
                      .|..:.| :..|.:|.:|.|..|....     .|.||||.::   .:...|....
Zfish   644 ----------CTPTSRPGEWYNPYVSSSGHQGRTSATQYVASRAVQRSLAIIRHAKQKKQKAKQY 698

  Fly   374 CAIFQKLGKCVAHSRGKCRKLHDKRQVAICVSFLRGECTKP--KCLLSHNVTLEKMPVCRYYLRG 436
            |..:.:.|||  :....|..:||..:||:|..||||.|.|.  .|..||.|..||||||.|:|:|
Zfish   699 CMYYNRFGKC--NHGNTCPYIHDPDKVAVCTRFLRGTCKKTDGTCPFSHKVAKEKMPVCSYFLKG 761

  Fly   437 VCVREDCPYLHKKLSSKTEICIDFVRGYCPLAAECNKRHEFSCPELERKGKCELPRCVFCKKSPS 501
            :|....|||.|..:|.|.|:|.||||||||...:|.|:|...||:....|.|  ||...||
Zfish   762 ICNNSSCPYSHVYVSRKAEVCEDFVRGYCPQGDKCKKKHTLVCPDFSSTGVC--PRGSKCK---- 820

  Fly   502 KRLAKVKSRPKLGSKPVAFTDTAKESSTADELPTSSRYFGSHKEPAEAILTRDDVEQKKPEAEDE 566
              |...:|:.:.||.  |....||::.|.|.|.:|                 |..:.:..|:...
Zfish   821 --LHHRQSKKRTGSN--ASYGAAKKACTRDVLRSS-----------------DAAQTQSSESTLA 864

  Fly   567 DQKEAGAPCPRRRPQLGTLPSFIPL 591
            |:   |:.|  .||:  .|||||.|
Zfish   865 DE---GSSC--SRPE--KLPSFISL 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZC3H3	NP_648230.1	YTH1	329..519	CDD:227416	74/200 (37%)
zc3h3	XP_689680.3	YTH1	<698..>802	CDD:227416	49/105 (47%)