DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZC3H3 and T26A8.4

DIOPT Version :9

Sequence 1:	NP_648230.1	Gene:	ZC3H3 / 38968	FlyBaseID:	FBgn0035900	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_501435.1	Gene:	T26A8.4 / 177643	WormBaseID:	WBGene00020827	Length:	574	Species:	Caenorhabditis elegans

Alignment Length:	175	Identity:	39/175 - (22%)
Similarity:	56/175 - (32%)	Gaps:	48/175 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   413 KPKCLLSHNVTLEKMPVCRYYLRGVCVRED-CPYLHKKLSS--KTEICIDFVRGYCPLAAECNKR 474
            ||:....|.       :|:::..|.|...| |.|.|:...|  :..:|..:...:|....:|...
Worm   161 KPRFQTEHQ-------ICKFFREGYCRDGDNCLYSHQAEDSLRRPVLCNFYANSFCKKGLQCLML 218

  Fly   475 H-EFSCPELERKGKCELPRCVFCKKSPSKRLAKVKSRPKLGSKPVAFTDTAK---ESSTADELPT 535
            | ||.|... .||:|....|.|                    ..|..||..:   |...|||
Worm   219 HGEFPCKSF-HKGQCNHDPCRF--------------------SHVPLTDYTRPIIEKILADE--- 259

  Fly   536 SSRYFGSHKEPAEAILTRD-DVEQKKPEAEDEDQKEAGAPCPRRR 579
                     |..:|...:. ...::.|.|.......|....||||
Worm   260 ---------EARQAHQAQQAQTYRQNPVANAAAAAAAAQVMPRRR 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZC3H3	NP_648230.1	YTH1	329..519	CDD:227416	23/109 (21%)
ZC3H3	NP_648230.1	ZnF_C3H1	425..447	CDD:214632	6/22 (27%)
T26A8.4	NP_501435.1	ZnF_C3H1	168..189	CDD:214632	7/27 (26%)
		ZnF_C3H1	196..221	CDD:214632	4/24 (17%)
		PHA03160	<347..437	CDD:165431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810