DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and STI1

DIOPT Version :9

Sequence 1:NP_001246673.1 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:NP_014670.1 Gene:STI1 / 854192 SGDID:S000005553 Length:589 Species:Saccharomyces cerevisiae


Alignment Length:467 Identity:94/467 - (20%)
Similarity:169/467 - (36%) Gaps:122/467 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 EKVRQSNAACQSGDFATAVLLYTDALQL-DPGNHILYSNRSAALLKQGQFTAALQDATQARDLCP 130
            |..:|.|||..:.|:..|:.|:|.|::: :..||:|||||||......:|:.||.||.:...:.|
Yeast     7 EYKQQGNAAFTAKDYDKAIELFTKAIEVSETPNHVLYSNRSACYTSLKKFSDALNDANECVKINP 71

  Fly   131 QWPKAYFRQGVALQCLGRYGEALAAFASGLAQEPSNKQLMAGLVEASLKSPLRAA---------- 185
            .|.|.|.|.|.|...||...||.:.:...|..:.|||....||.:.......|.|          
Yeast    72 SWSKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAKEGLDQVHRTQQARQAQPDLGLTQLF 136

  Fly   186 LEPTL-----QQLRTMQLQESPFVVSSV---------VGQELL---------------------- 214
            .:|.|     :..:|.::.:.|.:|:.:         :||:|.                      
Yeast   137 ADPNLIENLKKNPKTSEMMKDPQLVAKLIGYKQNPQAIGQDLFTDPRLMTIMATLMGVDLNMDDI 201

  Fly   215 --------------------QATQYSAAVTVLEAA--------------LRIGSCSLKLRGSVFS 245
                                .|...|.:.|..|.:              :.:.....|:......
Yeast   202 NQSNSMPKEPETSKSTEQKKDAEPQSDSTTSKENSSKAPQKEESKESEPMEVDEDDSKIEADKEK 266

  Fly   246 ALSSAHWALNQLDQAIGYMQQDLAVAKSLGDTAGECRAHGNLGSAYFSQGAHKEALTAHRYQLVL 310
            |..:..:...|.|:||.:..:...:.|.:       ....|..:|.:.:|.::.|::.....:..
Yeast   267 AEGNKFYKARQFDEAIEHYNKAWELHKDI-------TYLNNRAAAEYEKGEYETAISTLNDAVEQ 324

  Fly   311 AMKCK-DTQAAAAALTSLGHVYTASGD-------YPNALASHKQCVQLFKQLG------------ 355
            ..:.: |.:..:.:...:|:.|...||       |..:|..|:....|.|...            
Yeast   325 GREMRADYKVISKSFARIGNAYHKLGDLKKTIEYYQKSLTEHRTADILTKLRNAEKELKKAEAEA 389

  Fly   356 ----DRLQEAREIGNVGAVYLALGECEAALDCHSQHLRLARKLHDQVEEARAYSNLGSAHHQRRQ 416
                ::.:|||   ..|..|....:...|:..:::.::.|      .|:||.|||..:|..:...
Yeast   390 YVNPEKAEEAR---LEGKEYFTKSDWPNAVKAYTEMIKRA------PEDARGYSNRAAALAKLMS 445

  Fly   417 FTQAAA-CHEQV 427
            |.:|.| |::.:
Yeast   446 FPEAIADCNKAI 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_001246673.1 TPR_11 70..130 CDD:290150 23/60 (38%)
TPR repeat 98..128 CDD:276809 14/29 (48%)
TPR_11 101..164 CDD:290150 24/62 (39%)
TPR repeat 133..161 CDD:276809 9/27 (33%)
TPR repeat 243..269 CDD:276809 5/25 (20%)
TPR repeat 281..311 CDD:276809 4/29 (14%)
TPR_12 282..353 CDD:290160 13/78 (17%)
TPR_12 320..393 CDD:290160 16/95 (17%)
TPR repeat 321..349 CDD:276809 7/34 (21%)
TPR repeat 354..390 CDD:276809 6/51 (12%)
TPR_12 401..473 CDD:290160 10/28 (36%)
TPR repeat 401..429 CDD:276809 10/28 (36%)
TPR_7 403..438 CDD:289919 8/26 (31%)
TPR repeat 441..469 CDD:276809
TPR 467..752 CDD:223533
TPR repeat 482..509 CDD:276809
TPR repeat 522..549 CDD:276809
TPR repeat 561..595 CDD:276809
TPR repeat 600..630 CDD:276809
TPR repeat 642..669 CDD:276809
TPR_7 643..677 CDD:289919
TPR repeat 680..716 CDD:276809
TPR repeat 721..749 CDD:276809
TPR_7 723..758 CDD:289919
TPR repeat 801..829 CDD:276809
TPR_12 841..914 CDD:290160
TPR repeat 841..878 CDD:276809
TPR_12 882..949 CDD:290160
TPR repeat 883..913 CDD:276809
TPR 884..914 CDD:197478
TPR repeat 924..949 CDD:276809
TPR_12 964..1036 CDD:290160
TPR repeat 964..998 CDD:276809
TPR repeat 1004..1032 CDD:276809
TPR repeat 1043..1073 CDD:276809
TPR_12 1044..1112 CDD:290160
TPR_7 1046..1078 CDD:289919
TPR_12 1081..1153 CDD:290160
TPR repeat 1081..1109 CDD:276809
CHAT 1421..1718 CDD:289536
Treacle <1957..2287 CDD:281536
STI1NP_014670.1 PLN03088 5..>106 CDD:215568 36/98 (37%)
TPR repeat 5..33 CDD:276809 10/25 (40%)
TPR repeat 39..69 CDD:276809 14/29 (48%)
TPR repeat 74..102 CDD:276809 9/27 (33%)
STI1 138..193 CDD:407696 8/54 (15%)
3a0801s09 203..>573 CDD:273380 43/271 (16%)
TPR repeat 262..290 CDD:276809 5/27 (19%)
TPR repeat 294..324 CDD:276809 4/36 (11%)
TPR repeat 336..363 CDD:276809 5/26 (19%)
PLN03088 396..>549 CDD:215568 18/71 (25%)
TPR repeat 396..424 CDD:276809 6/30 (20%)
TPR repeat 429..459 CDD:276809 10/29 (34%)
TPR repeat 464..490 CDD:276809
STI1 527..581 CDD:407696
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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