DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and Ttc29

DIOPT Version :10

Sequence 1:NP_648228.2 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:NP_898919.3 Gene:Ttc29 / 73301 MGIID:1920551 Length:471 Species:Mus musculus


Alignment Length:344 Identity:89/344 - (25%)
Similarity:146/344 - (42%) Gaps:43/344 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   463 FHE--RQLAMALAARDKLGEGRACSNLGIVYQMLGSHDAALKLHQAHLGIARS-LGDRTG-MGKA 523
            ||:  .:|...:...|||.|.....:|  .:|.....|...||...:..:.|: ..:|.| ..:.
Mouse    77 FHKSFTELFALMEQWDKLREAAKAQSL--FWQQRPLEDQPDKLDNFYHYLTRAEAAERKGYYEEV 139

  Fly   524 YGNMARMA-HMAGSYEAAVKYHKQELAINQAM------NDRSAEAATHGNLAVAYQALGAHDAAL 581
            |.|:..:| :...|.:..|:.|..|...|.|.      ..:.|||.:|  :.:.::..|....|.
Mouse   140 YNNLYALACYFDNSEDKWVRNHFYERCFNIAQLIKADGGKKEAEAESH--MGLLFEEEGELLKAA 202

  Fly   582 THYRA--HLATARSLKDTAGEACALLNLGNC---------LSGR----QEYEEAVPHYESYLMLA 631
            .||.|  .|...|..||..|:   ||||..|         ||.|    ::|::|:........:|
Mouse   203 EHYEAFHELTHGRLWKDGTGQ---LLNLVACESLVRTYRLLSDRMLENKDYKQAIKILIKASEIA 264

  Fly   632 QELGDVAAEGKACHLLGYAHFSLGNYRAAV----RYYDQDLALAKDAQHRPNMGRAYCNLGLAHL 692
            :|..|.:.||:|.:.||.||.:.|.|..|:    ||  .:::.:.|..|  .:||||..:..|..
Mouse   265 REGNDRSMEGEASYYLGLAHLASGEYETALTVLNRY--SEISTSLDDDH--GLGRAYEAIAKALQ 325

  Fly   693 ALGHTAAALECQQLFLAVAHATNQLPAKFRALGNIGDILIRTGSHEEAIKLYQRQLALARAAGDR 757
            :.|.|..|:...:.|:.:|....|.....||...:|||....|.:.:|.:.:|:..:.|......
Mouse   326 SQGETTEAINYLEKFVTIARNNLQSLDMIRACTMLGDIYNEKGQYSKASEYFQQAFSTAMELMKT 390

  Fly   758 SM--EAAACGALGLAHRLM 774
            ::  |......:..||::|
Mouse   391 ALMDETKVHYGIARAHQMM 409

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_648228.2 PEP_TPR_lipo <78..751 CDD:274350 84/317 (26%)
TPR repeat 98..128 CDD:276809
TPR repeat 133..161 CDD:276809
TPR repeat 243..269 CDD:276809
TPR repeat 281..311 CDD:276809
TPR repeat 321..349 CDD:276809
TPR repeat 354..390 CDD:276809
TPR repeat 401..429 CDD:276809
TPR repeat 441..469 CDD:276809 2/7 (29%)
TPR repeat 482..509 CDD:276809 5/26 (19%)
TPR repeat 522..549 CDD:276809 7/27 (26%)
TPR 523..781 CDD:440225 74/280 (26%)
TPR repeat 561..595 CDD:276809 9/35 (26%)
TPR repeat 600..630 CDD:276809 10/42 (24%)
TPR repeat 642..669 CDD:276809 10/30 (33%)
TPR repeat 680..716 CDD:276809 10/35 (29%)
TPR repeat 721..749 CDD:276809 8/27 (30%)
TPR_12 801..865 CDD:315987
TPR repeat 801..829 CDD:276809
Spy 841..>1073 CDD:443119
TPR repeat 841..878 CDD:276809
TPR repeat 883..913 CDD:276809
TPR repeat 924..949 CDD:276809
TPR repeat 964..998 CDD:276809
COG4995 975..1718 CDD:444019
TPR repeat 1004..1032 CDD:276809
TPR repeat 1043..1073 CDD:276809
TPR repeat 1081..1109 CDD:276809
CHAT 1421..1718 CDD:432771
Ttc29NP_898919.3 TPR 1. /evidence=ECO:0000250|UniProtKB:Q8NA56 92..131 10/40 (25%)
TPR 2. /evidence=ECO:0000250|UniProtKB:Q8NA56 136..173 9/36 (25%)
TPR 3. /evidence=ECO:0000255 182..215 10/34 (29%)
LapB <234..381 CDD:442196 41/150 (27%)
TPR 4. /evidence=ECO:0000255 234..267 6/32 (19%)
TPR repeat 234..262 CDD:276809 5/27 (19%)
TPR 5. /evidence=ECO:0000255 274..307 11/34 (32%)
TPR repeat 275..308 CDD:276809 10/34 (29%)
TPR repeat 313..343 CDD:276809 9/29 (31%)
TPR 6. /evidence=ECO:0000255 314..347 10/32 (31%)
TPR 7. /evidence=ECO:0000255 354..387 9/32 (28%)
TPR repeat 354..380 CDD:276809 8/25 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 449..471
Blue background indicates that the domain is not in the aligned region.

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