DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and si:dkey-33c12.4

DIOPT Version :9

Sequence 1:NP_001246673.1 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:XP_021336269.1 Gene:si:dkey-33c12.4 / 560112 ZFINID:ZDB-GENE-030131-2527 Length:648 Species:Danio rerio


Alignment Length:411 Identity:91/411 - (22%)
Similarity:147/411 - (35%) Gaps:118/411 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 AKIAIVGEQLLNKMSQRDFSENEPECTPELPAANRALFLEKVRQSNAACQSGDFATAVLLYTDAL 92
            ||..:.||:.:|   ..||             ..|::.|..:  .|....||:...||..:|||:
Zfish   296 AKEEVNGEESVN---ANDF-------------ITRSVELAVI--GNEYAGSGNMEMAVKYFTDAI 342

  Fly    93 QLDPGNHILYSNRSAALLKQGQFTAALQDATQARDLCPQWPKAYFRQGVALQCLGRYGEALAAFA 157
            :.:|..:.|:.|||....|..|:..:|.||..|..:.|:|.|..:|:|.||..|.||.||...|.
Zfish   343 KHNPKEYKLFGNRSYCYEKMLQYEKSLTDAEIALSMNPKWIKGLYRKGRALVGLKRYNEARLTFG 407

  Fly   158 SGLAQEPSNKQLMAGLVEASLKSPLRAALEPTLQQLRTMQLQESPFVVSSVVGQELLQATQYSAA 222
            ..|..:.|.|.               ||.|  :.:::.|||.|..|....               
Zfish   408 EVLKLDSSCKD---------------AAEE--IMRVQLMQLMEMGFTKEQ--------------- 440

  Fly   223 VTVLEAALRIGSCSLKLRGSVFSALSSAHWALNQLDQAIGYMQQDLAVAKSLGDTAGECRAHGNL 287
                      .|.:|.:.|:|..||.|    |:.|.          .:|..|.....|       
Zfish   441 ----------SSNALIIHGTVERALES----LSGLS----------GLAPVLVPKENE------- 474

  Fly   288 GSAYFSQGAHKEALTAHRYQL--VLAMKCKDTQAAAAAL----TSLGHVYTASGDYPNALASHKQ 346
                |....:|......::.|  :...:.:.:...||.|    ..|..::.  ||..:::...| 
Zfish   475 ----FKSVQYKHPQPPAKFPLMPLPQNQPRPSMPTAAPLPPHSPELFPIWV--GDLVSSITGSK- 532

  Fly   347 CVQLFKQLGDRLQEAREIGNVGAV---------YLALGECEAALDCHSQH--------LRLARKL 394
            ...|||.:|:       |.||..:         |.:...||.|:...:.|        :|...::
Zfish   533 LYDLFKSVGN-------IHNVRVLPDRYCAFVNYTSKDSCEKAIQMFNGHAIDGTTLVVRYPDRI 590

  Fly   395 HDQVEEARAYSNLGSAHHQRR 415
            |.::..:|..|...|..:.::
Zfish   591 HTRLGMSRDASTESSGKNGKQ 611

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_001246673.1 TPR_11 70..130 CDD:290150 19/59 (32%)
TPR repeat 98..128 CDD:276809 10/29 (34%)
TPR_11 101..164 CDD:290150 24/62 (39%)
TPR repeat 133..161 CDD:276809 11/27 (41%)
TPR repeat 243..269 CDD:276809 6/25 (24%)
TPR repeat 281..311 CDD:276809 3/31 (10%)
TPR_12 282..353 CDD:290160 12/76 (16%)
TPR_12 320..393 CDD:290160 20/93 (22%)
TPR repeat 321..349 CDD:276809 7/31 (23%)
TPR repeat 354..390 CDD:276809 9/52 (17%)
TPR_12 401..473 CDD:290160 3/15 (20%)
TPR repeat 401..429 CDD:276809 3/15 (20%)
TPR_7 403..438 CDD:289919 2/13 (15%)
TPR repeat 441..469 CDD:276809
TPR 467..752 CDD:223533
TPR repeat 482..509 CDD:276809
TPR repeat 522..549 CDD:276809
TPR repeat 561..595 CDD:276809
TPR repeat 600..630 CDD:276809
TPR repeat 642..669 CDD:276809
TPR_7 643..677 CDD:289919
TPR repeat 680..716 CDD:276809
TPR repeat 721..749 CDD:276809
TPR_7 723..758 CDD:289919
TPR repeat 801..829 CDD:276809
TPR_12 841..914 CDD:290160
TPR repeat 841..878 CDD:276809
TPR_12 882..949 CDD:290160
TPR repeat 883..913 CDD:276809
TPR 884..914 CDD:197478
TPR repeat 924..949 CDD:276809
TPR_12 964..1036 CDD:290160
TPR repeat 964..998 CDD:276809
TPR repeat 1004..1032 CDD:276809
TPR repeat 1043..1073 CDD:276809
TPR_12 1044..1112 CDD:290160
TPR_7 1046..1078 CDD:289919
TPR_12 1081..1153 CDD:290160
TPR repeat 1081..1109 CDD:276809
CHAT 1421..1718 CDD:289536
Treacle <1957..2287 CDD:281536
si:dkey-33c12.4XP_021336269.1 PLN03088 258..>439 CDD:330826 52/177 (29%)
TPR repeat 348..378 CDD:276809 10/29 (34%)
TPR repeat 383..411 CDD:276809 11/27 (41%)
UBA 430..456 CDD:270456 9/50 (18%)
RRM <471..>614 CDD:223796 28/162 (17%)
RRM 519..584 CDD:214636 15/74 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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