DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and pins

DIOPT Version :10

Sequence 1:NP_648228.2 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:NP_524999.2 Gene:pins / 53569 FlyBaseID:FBgn0040080 Length:658 Species:Drosophila melanogaster


Alignment Length:374 Identity:117/374 - (31%)
Similarity:194/374 - (51%) Gaps:23/374 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 GQELLQATQYSAAVTVLEAALRIGSCSLKLRGSVFSALSSAHWALNQLDQAIGYMQQDLAVAKSL 274
            |:.|.:|....|.|...:||::.|:..|:...:::|.|.:|::.|...::|:.|.:.||.:|||:
  Fly    50 GERLCKAGDCRAGVAFFQAAIQAGTEDLRTLSAIYSQLGNAYFYLGDYNKAMQYHKHDLTLAKSM 114

  Fly   275 GDTAGECRAHGNLGSAYFSQGAHKEALTAHRYQLVLAMKCKDTQAAAAALTSLGHVYTASGDY-- 337
            .|..||.::.||||:.....|...||.......|.||.:..|..:...||.:||:||.|.|.:  
  Fly   115 NDRLGEAKSSGNLGNTLKVMGRFDEAAICCERHLTLARQLGDRLSEGRALYNLGNVYHAKGKHLG 179

  Fly   338 ---------------PNALASHKQCVQLFKQLGDRLQEAREIGNVGAVYLALGECEAALDCHSQH 387
                           ..|:..:::.::|.:.||||..:.|..||:|..|..||:.:||::.|.:.
  Fly   180 QRNPGKFGDDVKEALTRAVEFYQENLKLMRDLGDRGAQGRACGNLGNTYYLLGDFQAAIEHHQER 244

  Fly   388 LRLARKLHDQVEEARAYSNLGSAHHQRRQFTQAAACHEQVLRIAQALGDRSMEAAAYAGLGHAAR 452
            ||:||:..|:..|.||.||||::|....||..||..:::.|.:|..||:|.:||.:...||:...
  Fly   245 LRIAREFGDRAAERRANSNLGNSHIFLGQFEDAAEHYKRTLALAVELGEREVEAQSCYSLGNTYT 309

  Fly   453 CAGDASASKRFHERQLAMALAARDKLGEGRACSNLGIVYQMLGSHDAALKLHQAHLGIARSLGDR 517
            ...:.:.:..:|.|.||:|....|::||.|||.:||..:..:|.|:.|||..:.||.:|:.|.|.
  Fly   310 LLHEFNTAIEYHNRHLAIAQELGDRIGEARACWSLGNAHSAIGGHERALKYAEQHLQLAKELHDP 374

  Fly   518 TGMGKAYGNMARMAHMAGSYEAAVKYHKQELAINQAMNDRSAEAATHGN 566
            .|...|..|::.:..:.|..::.....::|  .....:|.||.    ||
  Fly   375 VGESTARVNISDLRKLLGMPDSEPSPTEEE--ARSTASDHSAS----GN 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_648228.2 PEP_TPR_lipo <78..751 CDD:274350 117/374 (31%)
TPR repeat 98..128 CDD:276809
TPR repeat 133..161 CDD:276809
TPR repeat 243..269 CDD:276809 7/25 (28%)
TPR repeat 281..311 CDD:276809 8/29 (28%)
TPR repeat 321..349 CDD:276809 9/44 (20%)
TPR repeat 354..390 CDD:276809 15/35 (43%)
TPR repeat 401..429 CDD:276809 11/27 (41%)
TPR repeat 441..469 CDD:276809 5/27 (19%)
TPR repeat 482..509 CDD:276809 11/26 (42%)
TPR repeat 522..549 CDD:276809 4/26 (15%)
TPR 523..781 CDD:440225 9/44 (20%)
TPR repeat 561..595 CDD:276809 2/6 (33%)
TPR repeat 600..630 CDD:276809
TPR repeat 642..669 CDD:276809
TPR repeat 680..716 CDD:276809
TPR repeat 721..749 CDD:276809
TPR_12 801..865 CDD:315987
TPR repeat 801..829 CDD:276809
Spy 841..>1073 CDD:443119
TPR repeat 841..878 CDD:276809
TPR repeat 883..913 CDD:276809
TPR repeat 924..949 CDD:276809
TPR repeat 964..998 CDD:276809
COG4995 975..1718 CDD:444019
TPR repeat 1004..1032 CDD:276809
TPR repeat 1043..1073 CDD:276809
TPR repeat 1081..1109 CDD:276809
CHAT 1421..1718 CDD:432771
pinsNP_524999.2 TPR 50..261 CDD:440225 65/210 (31%)
TPR repeat 83..109 CDD:276809 7/25 (28%)
TPR repeat 120..150 CDD:276809 9/29 (31%)
TPR 162..>373 CDD:440225 72/210 (34%)
TPR repeat 162..199 CDD:276809 9/36 (25%)
TPR repeat 219..246 CDD:276809 10/26 (38%)
TPR repeat 251..291 CDD:276809 15/39 (38%)
TPR repeat 296..326 CDD:276809 6/29 (21%)
TPR repeat 338..366 CDD:276809 11/27 (41%)
GoLoco 468..488 CDD:460481
GoLoco 552..573 CDD:460481
GoLoco 613..633 CDD:460481
Blue background indicates that the domain is not in the aligned region.

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