DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and CG1909

DIOPT Version :10

Sequence 1:NP_648228.2 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:NP_651928.1 Gene:CG1909 / 43800 FlyBaseID:FBgn0039911 Length:606 Species:Drosophila melanogaster


Alignment Length:467 Identity:111/467 - (23%)
Similarity:182/467 - (38%) Gaps:80/467 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 GQELLQATQYSAAVTVLEAALRIGSCSLKLRGSVFSALSSAHWALNQLDQAIGYMQQDLAVAKSL 274
            |:.|.:....:.||....:||: |:|..:....:...|..||....:..:||.:..|.|.:::.|
  Fly   101 GRRLYEQNNQTEAVRTWRSALK-GTCQREDCFQLLGYLYQAHMDWGKFREAIEFSHQQLGISEEL 164

  Fly   275 GDTAGECRAHGNLGSAYFSQGAHKEALTAHRYQLV--LAMKCKDTQAAAAALTSLGHVYTASGDY 337
            .........:.||..|:.|.|..:.:|:..|:.|.  ...||:   :....|| :..||...|.:
  Fly   165 DSPNMRAETYLNLSRAHASLGGLERSLSYARHSLYNECGTKCR---SGLVHLT-VARVYLEMGGF 225

  Fly   338 PNALASHKQCVQLFKQLGDRLQEAREIGNVGAVYLALGECEAALDCHSQHLRLARKLHDQVEEAR 402
            ..||...:...::...:||...|.:       ||:||.|....|..:.:....|.|.:| :..:.
  Fly   226 SRALEGLQGAYKIATAIGDPSLELQ-------VYVALSELFGRLQDNDKSATYASKAYD-LSRSL 282

  Fly   403 AYSNLGSAHHQRRQFTQAAACHEQVLRIAQALGDRSMEAAAYAGLGHAARCAGDASASKRFHERQ 467
            ...:|.|.||:       ||    :||:|.:|                 |..|:...::.:.:..
  Fly   283 QLGDLNSCHHR-------AA----LLRMAVSL-----------------RKQGELGDAQDYCKEA 319

  Fly   468 LAMALAARDKLGEGRACSNLGIVYQMLGSHDAALKLHQAHLGIARSLGDRTGMGKAYGNMARMAH 532
            ..::|.:.|:....|:...:|.:|:.....|.|.:.::..:|.:.|||||         ||:|..
  Fly   320 TKLSLISGDQATYTRSIRVMGDIYRNKMDMDRAFRQYEQAMGTSASLGDR---------MAQMEA 375

  Fly   533 MAGSYEAAVKYHKQELAIN---QAMNDRSAEAAT-----------HGNLAVAYQALGAHDAALTH 583
            |.|:.........|....|   ...|.|..|.|:           ...||:.|:|||..|...||
  Fly   376 MDGAARCLETLRLQNKICNCRPLEFNTRLLEVASSIGAKFLVRKIRCRLALIYRALGDEDQYNTH 440

  Fly   584 YRAHLATARSLKDTAGEACALLNLGNCLSGRQEYEEAVP-----HYE-SYLMLAQELGDVAAEGK 642
            :|....|..:|....| ||     |..|..|.|..||:|     |.. :|.:|.:...:......
  Fly   441 FRLANQTDAALGLNCG-AC-----GELLGLRPENLEALPCAHILHARCAYEILRRREKNAPRSCP 499

  Fly   643 ACHLL--GYAHF 652
            ||:.|  ...||
  Fly   500 ACNKLISSRTHF 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_648228.2 PEP_TPR_lipo <78..751 CDD:274350 111/467 (24%)
TPR repeat 98..128 CDD:276809
TPR repeat 133..161 CDD:276809
TPR repeat 243..269 CDD:276809 6/25 (24%)
TPR repeat 281..311 CDD:276809 8/31 (26%)
TPR repeat 321..349 CDD:276809 7/27 (26%)
TPR repeat 354..390 CDD:276809 9/35 (26%)
TPR repeat 401..429 CDD:276809 6/27 (22%)
TPR repeat 441..469 CDD:276809 2/27 (7%)
TPR repeat 482..509 CDD:276809 5/26 (19%)
TPR repeat 522..549 CDD:276809 6/26 (23%)
TPR 523..781 CDD:440225 41/152 (27%)
TPR repeat 561..595 CDD:276809 12/44 (27%)
TPR repeat 600..630 CDD:276809 11/35 (31%)
TPR repeat 642..669 CDD:276809 5/13 (38%)
TPR repeat 680..716 CDD:276809
TPR repeat 721..749 CDD:276809
TPR_12 801..865 CDD:315987
TPR repeat 801..829 CDD:276809
Spy 841..>1073 CDD:443119
TPR repeat 841..878 CDD:276809
TPR repeat 883..913 CDD:276809
TPR repeat 924..949 CDD:276809
TPR repeat 964..998 CDD:276809
COG4995 975..1718 CDD:444019
TPR repeat 1004..1032 CDD:276809
TPR repeat 1043..1073 CDD:276809
TPR repeat 1081..1109 CDD:276809
CHAT 1421..1718 CDD:432771
CG1909NP_651928.1 Rapsyn_N 89..168 CDD:431369 16/67 (24%)
LapB 92..386 CDD:442196 75/334 (22%)
TPR repeat 94..122 CDD:276809 5/20 (25%)
TPR repeat 127..164 CDD:276809 7/36 (19%)
TPR repeat 171..198 CDD:276809 7/26 (27%)
TPR repeat 211..237 CDD:276809 7/26 (27%)
TPR repeat 248..278 CDD:276809 10/37 (27%)
TPR repeat 293..321 CDD:276809 8/55 (15%)
TPR repeat 333..360 CDD:276809 5/26 (19%)
RING-H2_Rapsyn 452..503 CDD:438141 15/56 (27%)
Blue background indicates that the domain is not in the aligned region.

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