DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and Ttc29

DIOPT Version :10

Sequence 1:NP_648228.2 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:XP_063133962.1 Gene:Ttc29 / 291944 RGDID:1589777 Length:473 Species:Rattus norvegicus


Alignment Length:432 Identity:99/432 - (22%)
Similarity:160/432 - (37%) Gaps:110/432 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   790 LRQELGDLSGECRAHGHLGAVHMALC----------SWTNAVKCYQEQLERAQEQRDAAVEAQAH 844
            |.|.:..||.| ....|..:...::|          |:|.... ..||.::.:|      .|||.
  Rat    45 LEQNIKGLSKE-EVAAHRNSYKKSICVDMLRDGFHKSFTELFS-LMEQWDKLRE------AAQAR 101

  Fly   845 GNLGIARLNMAHYEAAIGCLEAQLGTLERVSLPSTQADRARALGHLGDCYAALGDYEEALKC--- 906
            ....:.|           .||.|...|:......|:|:.|...|:..:.|..|    .||.|   
  Rat   102 SLFWLQR-----------PLEDQPDKLDNFYHYLTKAEAAERKGYYEEVYNNL----YALACYFD 151

  Fly   907 -----------HDRQLQLA-----------------LGLTSHRDQE--------RAYRGLGQAR- 934
                       ::|..::|                 :||....:.|        .|:..|.|.| 
  Rat   152 NSEDKWVRNHFYERCFKIAQLIKVDGGKKEAEAEAHMGLLYEEEGELLKAAEHYEAFHELTQGRL 216

  Fly   935 --RALGQLPAALVCLEKRLVVAHELHSPEIKALAYGDLGHVHAALGN--HAQALNCLEHQRELAQ 995
              .|.||....:.|  :.||..:.|.|..:              |.|  :.||:..|....|:|:
  Rat   217 WKDATGQFLNLIAC--ESLVRTYRLLSDRM--------------LQNRDYKQAIKILIKASEIAR 265

  Fly   996 GLQDRALESDAMCALGQVQQRMGQHAQALELHRQDLEICTELSAPALQARALSNLGSVHESLGQQ 1060
            ...||::|.:|...||......|::..||.:..:..||.|.|.......||...:..|.:|.|:.
  Rat   266 EGNDRSMEGEASYYLGLAHLASGEYETALSVLDRYSEISTSLDDELSLGRAYEAMAKVLQSQGEM 330

  Fly  1061 AEALKCYERQLELSTDR---LAKAMACLALGRVHHQLEQHNQAVDYLRQGLASAQTTGKSE--EE 1120
            .||:|..|:.:.::.:.   |....||..||.::::..|:|:|.||.:|..::|....|:.  :|
  Rat   331 TEAIKYLEKFVVIARNNFKSLDVIQACTMLGDIYNEKGQYNKASDYFQQAFSTAMEVTKTTLMDE 395

  Fly  1121 AKIR------HQLGLALR---SSGDAEGAHIQL---ETAAQL 1150
            .|:.      ||:.|.:.   .|.|....:..|   ||..|:
  Rat   396 TKVHYGIARAHQMMLTMNGYIESADMNSLNCLLSWKETRTQV 437

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_648228.2 PEP_TPR_lipo <78..751 CDD:274350
TPR repeat 98..128 CDD:276809
TPR repeat 133..161 CDD:276809
TPR repeat 243..269 CDD:276809
TPR repeat 281..311 CDD:276809
TPR repeat 321..349 CDD:276809
TPR repeat 354..390 CDD:276809
TPR repeat 401..429 CDD:276809
TPR repeat 441..469 CDD:276809
TPR repeat 482..509 CDD:276809
TPR repeat 522..549 CDD:276809
TPR 523..781 CDD:440225
TPR repeat 561..595 CDD:276809
TPR repeat 600..630 CDD:276809
TPR repeat 642..669 CDD:276809
TPR repeat 680..716 CDD:276809
TPR repeat 721..749 CDD:276809
TPR_12 801..865 CDD:315987 11/73 (15%)
TPR repeat 801..829 CDD:276809 6/37 (16%)
Spy 841..>1073 CDD:443119 63/275 (23%)
TPR repeat 841..878 CDD:276809 8/36 (22%)
TPR repeat 883..913 CDD:276809 8/43 (19%)
TPR repeat 924..949 CDD:276809 9/35 (26%)
TPR repeat 964..998 CDD:276809 7/35 (20%)
COG4995 975..1718 CDD:444019 53/195 (27%)
TPR repeat 1004..1032 CDD:276809 6/27 (22%)
TPR repeat 1043..1073 CDD:276809 9/29 (31%)
TPR repeat 1081..1109 CDD:276809 10/27 (37%)
CHAT 1421..1718 CDD:432771
Ttc29XP_063133962.1 None
Blue background indicates that the domain is not in the aligned region.

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