DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and Ttc12

DIOPT Version :10

Sequence 1:NP_648228.2 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:NP_766358.1 Gene:Ttc12 / 235330 MGIID:2444588 Length:704 Species:Mus musculus


Alignment Length:219 Identity:34/219 - (15%)
Similarity:73/219 - (33%) Gaps:77/219 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 ESVHDVSKVTDPLQKAKRELDNVEIKEKQKKQKNQNETSEKETKKFSTVYEKFNDTIKELDRVSG 79
            :.:.::..:|:.|:...|....:|.||:.:.|         .||..:.     :|...||::.:|
Mouse    23 DHLRNLKALTEKLRLETRRPSYLEWKERVEAQ---------NTKGLAV-----SDGSTELEKDAG 73

  Fly    80 TCPIRPAIPFTPPKEKVEPIYHNECNFDDKAHLGVSDSALFVQGFDTSHPRHEIKTALWNHFSSC 144
               ::|.   ..|:..:|         |.:...|....:..:.|||                   
Mouse    74 ---LKPR---ATPQRTIE---------DSQMTAGNGLISRSLGGFD------------------- 104

  Fly   145 GKVYLIYVPIACSTGASVGYAFIDMKNETKGLTLNGSHLGGRKIDVMFAIDREEFYFSSNLKHCQ 209
                            ::..|.:.::.|...:.:....|..:.:.:...|::        ||..|
Mouse   105 ----------------NIDEALVWLRKELMEMRIQDQQLARQLMRLRGDINK--------LKVEQ 145

  Fly   210 RCRNYRPWLVLKAMSDACFEYHQR 233
            .|..:|     :.::||.|...:|
Mouse   146 TCHLHR-----RMLNDATFGLEER 164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_648228.2 PEP_TPR_lipo <78..751 CDD:274350 22/156 (14%)
TPR repeat 98..128 CDD:276809 5/29 (17%)
TPR repeat 133..161 CDD:276809 0/27 (0%)
TPR repeat 243..269 CDD:276809
TPR repeat 281..311 CDD:276809
TPR repeat 321..349 CDD:276809
TPR repeat 354..390 CDD:276809
TPR repeat 401..429 CDD:276809
TPR repeat 441..469 CDD:276809
TPR repeat 482..509 CDD:276809
TPR repeat 522..549 CDD:276809
TPR 523..781 CDD:440225
TPR repeat 561..595 CDD:276809
TPR repeat 600..630 CDD:276809
TPR repeat 642..669 CDD:276809
TPR repeat 680..716 CDD:276809
TPR repeat 721..749 CDD:276809
TPR_12 801..865 CDD:315987
TPR repeat 801..829 CDD:276809
Spy 841..>1073 CDD:443119
TPR repeat 841..878 CDD:276809
TPR repeat 883..913 CDD:276809
TPR repeat 924..949 CDD:276809
TPR repeat 964..998 CDD:276809
COG4995 975..1718 CDD:444019
TPR repeat 1004..1032 CDD:276809
TPR repeat 1043..1073 CDD:276809
TPR repeat 1081..1109 CDD:276809
CHAT 1421..1718 CDD:432771
Ttc12NP_766358.1 PLN03088 104..>254 CDD:215568 14/109 (13%)
TPR 1 105..138 3/32 (9%)
TPR repeat 105..133 CDD:276809 3/27 (11%)
TPR repeat 138..168 CDD:276809 10/40 (25%)
TPR 2 139..172 9/39 (23%)
TPR 3 173..206
TPR repeat 173..198 CDD:276809
Blue background indicates that the domain is not in the aligned region.

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