DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43163 and ags-3

DIOPT Version :9

Sequence 1:NP_001246673.1 Gene:CG43163 / 38966 FlyBaseID:FBgn0262719 Length:2523 Species:Drosophila melanogaster
Sequence 2:NP_741787.1 Gene:ags-3 / 180801 WormBaseID:WBGene00000092 Length:579 Species:Caenorhabditis elegans


Alignment Length:436 Identity:95/436 - (21%)
Similarity:174/436 - (39%) Gaps:111/436 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 GQELLQATQYSAAVTVLEAALRIGSCSLKLRGSVFSALSSAHWALNQLDQAIGYMQQDLAVAKSL 274
            |:.|.:..:|...:.:|:.||.:|:....|..:::..|.:||..|...:||:.:...|:.|.:.|
 Worm    13 GERLFRMQKYEKGIDLLKKALEVGTDDFSLLSAIYCQLGNAHTMLKDYEQALKFHTYDILVERLL 77

  Fly   275 GDTAGECRAHGNLGSAYFSQGAHKEALTAHRYQLVLAMKCKDTQAAAAALTSLGHVYTASGDYPN 339
            |:..||.::..|||:.:..:||:.:|||....||..|                            
 Worm    78 GNKEGEAKSCANLGNIFKMKGAYNDALTFTFKQLDFA---------------------------- 114

  Fly   340 ALASHKQCVQLFKQLGDRLQEAREIGNVGAVYLALGECEAALDCHSQHLRLARKLHDQVEEARAY 404
                        ::||||:.::|...|:..:|:..|.|                           
 Worm   115 ------------EELGDRVLKSRAYYNIATIYVERGRC--------------------------- 140

  Fly   405 SNLGSAHHQRRQFTQAAACHEQVLRIAQALGDRSMEAAAYAGLGHAARCAGDASASKRFHERQLA 469
                                            ..:|||........|....|...:.::....|.
 Worm   141 --------------------------------TKLEAAEEKNDAKNAEATSDFENAAKYFMLNLE 173

  Fly   470 MALAARDKLGEGRACSNLGIVYQMLGSHDAALKLHQAHLGIARSLGDRTGMGKAYGNMARMAHMA 534
            |:..:.|.|..||...:||..|..||.:|.::..|:..|.:::..|||..|.:|:.|:|....:.
 Worm   174 MSEKSEDALTMGRCYGSLGNTYYCLGDYDQSIHFHKLRLELSQQYGDRASMRRAHANIANCHALK 238

  Fly   535 GSYEAAVKYHKQELAINQA--MNDRSAEAATHGNLAVAYQALGAHDAALTHYRAHLATARSLKDT 597
            .:...|::::|  ||.|.|  :.:::.||....:||.|.........|:|:::.||..||||:|.
 Worm   239 SNMPLAIQHYK--LAYNLAIEIGNKTEEAQMAYSLANALYIGKEVQKAITYFQRHLKIARSLEDI 301

  Fly   598 AGEACALLNLGNCLSGRQEYEEAVPHYESYLMLAQ----ELGDVAA 639
            :|:..:..:|....:...|..:|:    .:|:||:    ::.|.:|
 Worm   302 SGQLRSYYSLALSFNNLCERRKAL----YFLVLAKRSSLQVNDTSA 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43163NP_001246673.1 TPR_11 70..130 CDD:290150
TPR repeat 98..128 CDD:276809
TPR_11 101..164 CDD:290150
TPR repeat 133..161 CDD:276809
TPR repeat 243..269 CDD:276809 7/25 (28%)
TPR repeat 281..311 CDD:276809 10/29 (34%)
TPR_12 282..353 CDD:290160 11/70 (16%)
TPR_12 320..393 CDD:290160 9/72 (13%)
TPR repeat 321..349 CDD:276809 0/27 (0%)
TPR repeat 354..390 CDD:276809 9/35 (26%)
TPR_12 401..473 CDD:290160 7/71 (10%)
TPR repeat 401..429 CDD:276809 0/27 (0%)
TPR_7 403..438 CDD:289919 0/34 (0%)
TPR repeat 441..469 CDD:276809 4/27 (15%)
TPR 467..752 CDD:223533 50/179 (28%)
TPR repeat 482..509 CDD:276809 8/26 (31%)
TPR repeat 522..549 CDD:276809 5/26 (19%)
TPR repeat 561..595 CDD:276809 11/33 (33%)
TPR repeat 600..630 CDD:276809 4/29 (14%)
TPR repeat 642..669 CDD:276809
TPR_7 643..677 CDD:289919
TPR repeat 680..716 CDD:276809
TPR repeat 721..749 CDD:276809
TPR_7 723..758 CDD:289919
TPR repeat 801..829 CDD:276809
TPR_12 841..914 CDD:290160
TPR repeat 841..878 CDD:276809
TPR_12 882..949 CDD:290160
TPR repeat 883..913 CDD:276809
TPR 884..914 CDD:197478
TPR repeat 924..949 CDD:276809
TPR_12 964..1036 CDD:290160
TPR repeat 964..998 CDD:276809
TPR repeat 1004..1032 CDD:276809
TPR repeat 1043..1073 CDD:276809
TPR_12 1044..1112 CDD:290160
TPR_7 1046..1078 CDD:289919
TPR_12 1081..1153 CDD:290160
TPR repeat 1081..1109 CDD:276809
CHAT 1421..1718 CDD:289536
Treacle <1957..2287 CDD:281536
ags-3NP_741787.1 TPR_11 7..65 CDD:290150 14/51 (27%)
TPR repeat 9..34 CDD:276809 5/20 (25%)
TPR repeat 39..79 CDD:276809 10/39 (26%)
TPR repeat 149..173 CDD:276809 2/23 (9%)
TPR_12 182..255 CDD:290160 23/74 (31%)
TPR repeat 186..213 CDD:276809 8/26 (31%)
TPR repeat 218..254 CDD:276809 11/37 (30%)
TPR_12 226..297 CDD:290160 19/72 (26%)
TPR repeat 265..293 CDD:276809 7/27 (26%)
GoLoco 417..437 CDD:280368
GoLoco 464..486 CDD:214645
GoLoco 511..533 CDD:214645
GoLoco 549..571 CDD:214645
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D321819at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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