DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43163 and SUGT1

DIOPT Version :9

Sequence 1:	NP_001246673.1	Gene:	CG43163 / 38966	FlyBaseID:	FBgn0262719	Length:	2523	Species:	Drosophila melanogaster
Sequence 2:	NP_001124384.1	Gene:	SUGT1 / 10910	HGNCID:	16987	Length:	365	Species:	Homo sapiens

Alignment Length:	71	Identity:	20/71 - (28%)
Similarity:	31/71 - (43%)	Gaps:	0/71 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 TDALQLDPGNHILYSNRSAALLKQGQFTAALQDATQARDLCPQWPKAYFRQGVALQCLGRYGEAL 153
            |.||:..|.:...|..|:...:..|.:..|:.||.::.:|.|....|..|:|:.......|..||
Human    35 TKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAAL 99

  Fly   154 AAFASG 159
            ..|..|
Human   100 ETFTEG 105

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43163	NP_001246673.1	TPR_11	70..130	CDD:290150	11/40 (28%)
		TPR repeat	98..128	CDD:276809	6/29 (21%)
		TPR_11	101..164	CDD:290150	16/59 (27%)
		TPR repeat	133..161	CDD:276809	8/27 (30%)
		TPR repeat	243..269	CDD:276809
		TPR repeat	281..311	CDD:276809
		TPR_12	282..353	CDD:290160
		TPR_12	320..393	CDD:290160
		TPR repeat	321..349	CDD:276809
		TPR repeat	354..390	CDD:276809
		TPR_12	401..473	CDD:290160
		TPR repeat	401..429	CDD:276809
		TPR_7	403..438	CDD:289919
		TPR repeat	441..469	CDD:276809
		TPR	467..752	CDD:223533
		TPR repeat	482..509	CDD:276809
		TPR repeat	522..549	CDD:276809
		TPR repeat	561..595	CDD:276809
		TPR repeat	600..630	CDD:276809
		TPR repeat	642..669	CDD:276809
		TPR_7	643..677	CDD:289919
		TPR repeat	680..716	CDD:276809
		TPR repeat	721..749	CDD:276809
		TPR_7	723..758	CDD:289919
		TPR repeat	801..829	CDD:276809
		TPR_12	841..914	CDD:290160
		TPR repeat	841..878	CDD:276809
		TPR_12	882..949	CDD:290160
		TPR repeat	883..913	CDD:276809
		TPR	884..914	CDD:197478
		TPR repeat	924..949	CDD:276809
		TPR_12	964..1036	CDD:290160
		TPR repeat	964..998	CDD:276809
		TPR repeat	1004..1032	CDD:276809
		TPR repeat	1043..1073	CDD:276809
		TPR_12	1044..1112	CDD:290160
		TPR_7	1046..1078	CDD:289919
		TPR_12	1081..1153	CDD:290160
		TPR repeat	1081..1109	CDD:276809
		CHAT	1421..1718	CDD:289536
		Treacle	<1957..2287	CDD:281536
SUGT1	NP_001124384.1	TPR 1	11..44		4/8 (50%)
		PLN03088	21..365	CDD:215568	20/71 (28%)
		TPR repeat	44..74	CDD:276809	6/29 (21%)
		TPR 2	45..78		8/32 (25%)
		TPR 3	79..112		8/27 (30%)
		TPR repeat	79..107	CDD:276809	8/27 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900