DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6983 and C20orf27

DIOPT Version :9

Sequence 1:	NP_001286984.1	Gene:	CG6983 / 38964	FlyBaseID:	FBgn0035896	Length:	180	Species:	Drosophila melanogaster
Sequence 2:	NP_001034229.1	Gene:	C20orf27 / 54976	HGNCID:	15873	Length:	199	Species:	Homo sapiens

Alignment Length:	177	Identity:	59/177 - (33%)
Similarity:	85/177 - (48%)	Gaps:	31/177 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NVEHQDHHVHFDTNTVKDDFESDSCV-TYQRSGDTIVVSLGFLQIRHRYLIELKLPT--SLFGDA 69
            :.|....|||||...      .||.| ..|.|..:.:|.:|||:|.|||.|...||.  .|..|.
Human    47 DAEGSHSHVHFDEKL------HDSVVMVTQESDSSFLVKVGFLKILHRYEITFTLPPVHRLSKDV 105

  Fly    70 KTLASKFEPVISATPSLHCRITEF----EGTKHDEHDFFEMKIEFFAYKEKLLREVLHIVSSSNA 130
            :.     .||    ||||.::...    ||        :.:|.|:.|:||.:|:|.:.:......
Human   106 RE-----APV----PSLHLKLLSVVPVPEG--------YSVKCEYSAHKEGVLKEEILLACEGGT 153

  Fly   131 KELLQLVIAARVLGKGKGTPMLRTGIHCIGVERDDDESEASDFAGFD 177
            ...:::.:.|||:.:..|||||..|:.|:|.|.:.| ||.||:.|||
Human   154 GTCVRVTVQARVMDRHHGTPMLLDGVKCVGAELEYD-SEHSDWHGFD 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6983	NP_001286984.1	DUF4517	14..176	CDD:373468	55/168 (33%)
C20orf27	NP_001034229.1	DUF4517	53..198	CDD:291667	55/168 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160420
Domainoid	1	1.000	73	1.000	Domainoid score	I9279
eggNOG	1	0.900	-	-		E1_2CAZT
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	76	1.000	Inparanoid score	I5264
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48489
OrthoDB	1	1.010	-	-		D1350523at2759
OrthoFinder	1	1.000	-	-		FOG0007238
OrthoInspector	1	1.000	-	-		oto88861
orthoMCL	1	0.900	-	-		OOG6_109221
Panther	1	1.100	-	-	LDO	PTHR13287
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5624
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.800