DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Unr and si:dkeyp-121d4.3

DIOPT Version :9

Sequence 1:	NP_001137912.1	Gene:	Unr / 38963	FlyBaseID:	FBgn0263352	Length:	1057	Species:	Drosophila melanogaster
Sequence 2:	XP_009305353.1	Gene:	si:dkeyp-121d4.3 / 100004621	ZFINID:	ZDB-GENE-130530-962	Length:	2019	Species:	Danio rerio

Alignment Length:	688	Identity:	148/688 - (21%)
Similarity:	246/688 - (35%)	Gaps:	207/688 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 PYTKDDVEGNVNLRAGDKVSFQIATNQRGNLGACHIRLENPAQPVKYRGVVCSMKESFGFIERAD 364
            |..|.|........|...::.:||..:  |:.|...|       .:..||:..:..:.|||||.|
Zfish   244 PQKKKDQSATKETEASKLLAAKIAAFK--NMSASTPR-------GRSLGVISFIGNNCGFIERED 299

  Fly   365 VVKEIFFHFSEAEGN-VELRPGDDVEFTIQTRSVSGSGDPTNPNMLQSKMQSASVPPQGREFACN 428
             :|:..|.|....|| ..|.||..|.||:                         |...|::.|.:
Zfish   300 -LKKFSFVFDAFIGNRTLLVPGVKVHFTV-------------------------VRNLGKDCAVD 338

  Fly   429 ITRLAPGSVIFEDVDSTVYKGQVLKSLDRNNPVRQNNDPLPGRIRYRALDYSEVEVPFGDKDQKG 493
            : ::|||..  :|:|||||:|.|:.|| .:...::.|   .|.|| ..:....:::|:...|.
Zfish   339 V-KVAPGGT--DDIDSTVYEGVVITSL-YDEGAKETN---LGCIR-TIISTDPIKLPYSKADT-- 393

  Fly   494 DFTLRHGDWVQFLLATDRRDQLQRATSI-ALLDETFKVSGEKREQGTIASLKEGFGFLRCVERQA 557
            :.||...|.|:|.|.|:...:.||||:| ..:.:||:::.|.||.|.|.|..:| ......|:..
Zfish   394 NLTLLLYDRVEFQLLTNVITKEQRATNIKPKIPDTFQLTKEVREMGVIMSKTDG-NLTIMTEKHD 457

  Fly   558 RLFFHFTEVLDTSREIDINDEVEFTVIQEPGLAYNNSRLQAIRIKHLPPNSVQFETLVASN---- 618
            .|.....:.| |..|:::.||||.||.      ..:...:|||:|.||..||.|......|
Zfish   458 NLAASAADSL-TDEELNVMDEVELTVF------IVDDTKKAIRLKKLPDGSVTFNQQAKGNDKWK 515

  Fly   619 --------------IEGCVTREAPKSPIKSQDRVE------GGVITYEHADVKKTIMYFLKDCEK 663
                          .||.|.|.|.|........::      |.::|......:|.:.:.|.|...
Zfish   516 PVTTEANCNISSEKYEGTVIRIASKESSTLDKEMDCQLPTLGLLVTTLEEGTEKRLSFKLGDVMS 580

  Fly   664 PPRI--GERVRFDIYMVK-RNKECIAVNVQ---QVSLHQQQQQQQQQLHLNQSNAGANINQNDQL 722
            ...:  |::|:|:|.... .|:|| ||||:   :..|...::|::
Zfish   581 KATMMNGDKVQFNICSNSVTNEEC-AVNVEILPETFLSDTEEQRK-------------------- 624

  Fly   723 GGLSNGISSSSSNASLQNGYVMHGSPGGSTSSVGSNNPVHLDEFKMENNNHAGSDAGQVYRGFIA 787
                                                                        .|.:.
Zfish   625 ------------------------------------------------------------IGLVI 629

  Fly   788 VMKENFGFIETLSHDEEVFFHFSNYMGNPNWLELGQEVEYTLARNGNTSVSGNCLPAENVRMLPK 852
            .:.:..|:|:| ..:.::.|.....|.:.. |.|.::||:||..|
Zfish   630 KLDDKCGYIKT-QQEPQLLFDLCEVMEDAK-LALSEKVEFTLVPN-------------------- 672

  Fly   853 NSIPQPAVLETTHNGVVARPLRCINPDQQEYAGLIEILDELRTTVISQHEFGITSLVNKRDLLQK 917
                     |....|..|..:|.:|......|..:|...     |..:.:..|..|.:.:|:.|:
Zfish   673 ---------EEVEGGKQAVRIRRLNESVFTSAPKLEAFG-----VKEKKKMTIKLLKDPKDIKQE 723

  Fly   918 G-----DLVSFRIDESGRAACVNAVRQKKRATVDSIKG 950
            .     |..|..:....:|:.||.::::.....::.||
Zfish   724 AKTEEKDSDSMNVHRPNKASSVNDLKKESVVKQENAKG 761

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Unr	NP_001137912.1	CSP	188..251	CDD:214633
		S1_like	347..395	CDD:299122	19/48 (40%)
		CSP	537..604	CDD:214633	19/66 (29%)
		S1_like	790..834	CDD:299122	12/43 (28%)
		CSP	942..1006	CDD:214633	2/9 (22%)
si:dkeyp-121d4.3	XP_009305353.1	Cytadhesin_P30	<81..225	CDD:284643
		RHOD	<154..>193	CDD:294087
		SGNH_hydrolase	1830..2003	CDD:238141
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582279
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12913
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940