DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and AT1G04360

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_171931.1	Gene:	AT1G04360 / 839540	AraportID:	AT1G04360	Length:	381	Species:	Arabidopsis thaliana

Alignment Length:	251	Identity:	51/251 - (20%)
Similarity:	84/251 - (33%)	Gaps:	51/251 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 QLCKICA---ENDKDIRIEP-CGHLLCTPCLTSWQVDSEGQG---CPFCRAEIKGTEQIVVDAFD 424
            |.|.:|.   :.|:.:||.| |.|:....|:..|.     ||   ||.||..:.......:|...
plant   132 QECSVCLNEFQEDEKLRIIPNCCHVFHIDCIDIWL-----QGNANCPLCRTSVSCEASFTLDLIS 191

  Fly   425 PRKQHNRNVTNGRQQQQE-------EDDTEDI------GDFNIATSSLHALSTSSTVAAEKHSPH 476
            .......|..:.|.:..|       :||...|      |:...:..::..|:....|.:.:.|..
plant   192 APSSPRENSPHSRNRNLEPGLVLGGDDDFVVIELGASNGNNRESVRNIDFLTEQERVTSNEVSTG 256

  Fly   477 TSPRLGRRSTTPSLMAVQN-DLYAGGTPTLSLPSSSCSSI--------------AAASTSSSSSL 526
            .||    :|.:|..:...| .:|........:.|.....|              ...|.|..||:
plant   257 NSP----KSVSPLPIKFGNRGMYKKERKFHKVTSMGDECIDTRGKDGHFGEIQPIRRSISMDSSV 317

  Fly   527 ASVATVAASTSSSQHQQPQPSAPPASAVLSNGGGGGG-------GGGASSSQKNTN 575
            .....:|.....|:..:..|.|.......|:|||...       ..|:|.:.|:::
plant   318 DRQLYLAVQEEISRRNRQIPVAGDGEDSSSSGGGNSRVMKRCFFSFGSSRTSKSSS 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176
		zf-C3HC4_3	367..415	CDD:290631	17/54 (31%)
		UBA_Cbl_like	834..873	CDD:270503
AT1G04360	NP_171931.1	zf-RING_2	133..176	CDD:290367	14/47 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910