DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and ATL15

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_173666.1	Gene:	ATL15 / 838856	AraportID:	AT1G22500	Length:	381	Species:	Arabidopsis thaliana

Alignment Length:	231	Identity:	49/231 - (21%)
Similarity:	80/231 - (34%)	Gaps:	69/231 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 QAYNPDLSSAV--QSPTEDHITVTQEQYELYCEMGSTFQLCKICA---ENDKDIRIEP-CGHLLC 389
            |...|.|.::|  ..||..:.||..      ..:|.....|.:|.   |:|:.:|:.| |.|:..
plant    84 QTTEPGLDASVIETFPTFPYSTVKT------LRIGKEALECPVCLNEFEDDETLRLIPQCCHVFH 142

  Fly   390 TPCLTSWQVDSEGQGCPFCRAEI------------------KGTEQIVVDAFDPRKQHNRNVTNG 436
            ..|:.:| :.|: ..||.|||.:                  .|...:.....|.||   |.:|:
plant   143 PGCIDAW-LRSQ-TTCPLCRANLVPVPGESVSSEIPGLARETGQNSLRTPIDDNRK---RVLTS- 201

  Fly   437 RQQQQEEDDTEDIGDFNIATSSLHALSTSSTVAAEKHSPHTSPRLGRRSTTPSLMAVQNDLYAGG 501
             ..::..|.....|:.::...|:    ::....||.:||.:||                     |
plant   202 -PDERLIDSVAWTGNQSMPRKSM----STGWKLAELYSPASSP---------------------G 240

  Fly   502 TP-------TLSLPSSSCSSIAAASTSSSSSLASVA 530
            .|       ||.||......:..:|.....|...:|
plant   241 QPEENLDRYTLRLPQEIHDQLVNSSLGKQGSKGQLA 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176	3/8 (38%)
		zf-C3HC4_3	367..415	CDD:290631	16/69 (23%)
		UBA_Cbl_like	834..873	CDD:270503
ATL15	NP_173666.1	RAD18	116..>217	CDD:227719	24/107 (22%)
ATL15	NP_173666.1	RING-H2_EL5_like	117..160	CDD:319375	13/44 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910