DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and ATCRT1

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_200445.1	Gene:	ATCRT1 / 835734	AraportID:	AT5G56340	Length:	396	Species:	Arabidopsis thaliana

Alignment Length:	249	Identity:	56/249 - (22%)
Similarity:	80/249 - (32%)	Gaps:	80/249 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   284 SCTRLGQWAIGYVTAEGEILQTIPQNKSLCQALLDGHREGFYLYPDGQAYNPDLSSAVQS-PTED 347
            |.|.||.:.||            |....|.|.|.:..       |:.|...|....||:: ||..
plant   207 SLTSLGDYFIG------------PGLDLLLQHLAEND-------PNRQGTPPARKEAVEALPTVK 252

  Fly   348 HITVTQEQYELYCEMGSTFQLCKICA---ENDKDIRIEPCGHLLCTPCLTSW-QVDSEGQGCPFC 408
            .:...|               |.:|.   |...:.:..||.|.....|:..| ::.|   .||.|
plant   253 IMEPLQ---------------CSVCLDDFEKGTEAKEMPCKHKFHVRCIVPWLELHS---SCPVC 299

  Fly   409 RAEIKGTEQIVVDAFDPRKQHNRNVTNGRQQQQEEDD--TEDIGDFNIATSSLHALSTSSTVAAE 471
            |.|:..:    .|..|..|..:..|...|..::..:.  .|::|:                 |..
plant   300 RFELPSS----ADDDDETKTDSERVLRTRNVRETSNGNVVENVGN-----------------ADR 343

  Fly   472 KHSPHTSPRLGRRSTTPSLMAVQNDLYAGGTPTLSLPSSSCSSIAAASTSSSSS 525
            ..........|||.:.|             .|...|.|||.||  ::|||.|.|
plant   344 GREDEVRSGNGRRFSFP-------------WPFSGLFSSSSSS--SSSTSGSQS 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176	13/55 (24%)
		zf-C3HC4_3	367..415	CDD:290631	14/51 (27%)
		UBA_Cbl_like	834..873	CDD:270503
ATCRT1	NP_200445.1	zinc_ribbon_9	8..39	CDD:405118
		RING-H2_RNF181	258..303	CDD:319583	14/62 (23%)
		HRD1	<259..359	CDD:227568	25/123 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910