DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and AT5G46650

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_199477.1	Gene:	AT5G46650 / 834708	AraportID:	AT5G46650	Length:	289	Species:	Arabidopsis thaliana

Alignment Length:	203	Identity:	42/203 - (20%)
Similarity:	70/203 - (34%)	Gaps:	57/203 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 QAYNPDLSSAVQSPTEDHI-------------TVTQEQYELYCEMGSTFQLCKICAENDKDI--R 380
            ||....:...|....|.||             .:.:::|.|.|      .:|.:..|.:..:  .
plant    72 QAQQEPVQPPVNPGLEPHIIQSYPLFPFSSVKDLREDKYGLEC------AICLLEFEEEHILLRL 130

  Fly   381 IEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEI-----KGTEQIVVDAFDPRKQHNRNVTNGRQQQ 440
            :..|.|:....|:..|.  ...:.||.||..:     :..::::::........||:
plant   131 LTTCYHVFHQECIDQWL--ESNKTCPVCRRNLDPNAPENIKELIIEVIQENAHENRD-------- 185

  Fly   441 QEEDDTEDIGDFNIATSSLHALSTSSTVAAEKHSPHTSPRLGRRSTTPSLMAVQN-----DLYAG 500
            ||:          .:||:...||..|:...|: ...|.|....||.|.....|:|     |.|
plant   186 QEQ----------TSTSNEVMLSRQSSGNNER-KIETLPDKFSRSKTTGHSIVRNKPEEEDRY-- 237

  Fly   501 GTPTLSLP 508
               ||.||
plant   238 ---TLRLP 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176	2/8 (25%)
		zf-C3HC4_3	367..415	CDD:290631	10/54 (19%)
		UBA_Cbl_like	834..873	CDD:270503
AT5G46650	NP_199477.1	zf-RING_2	113..157	CDD:290367	9/51 (18%)
AT5G46650	NP_199477.1	zf-rbx1	<114..157	CDD:289448	9/50 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910