DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and AT5G17600

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_197262.1	Gene:	AT5G17600 / 831626	AraportID:	AT5G17600	Length:	362	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	65/314 - (20%)
Similarity:	105/314 - (33%)	Gaps:	93/314 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 IGYVTAEGEILQTIPQNKSLCQALLDGHREGFY-----LYPDGQAYNPDLSSAVQSPTEDHITVT 352
            :.|.|...:......|..|.....|:.:.|||:     :..:|...|   .|.::|       :|
plant    72 VSYYTLISKYCHRHHQTSSSETLNLNHNGEGFFSSTQRISTNGDGLN---ESMIKS-------IT 126

  Fly   353 QEQYELYCEMGSTF---QLCKICA---ENDKDIRIEP-CGHLLCTPCLTSWQVDSEGQGCPFCRA 410
            ..:|    :.|..|   ..|.:|.   |.::.:|:.| |.|....||:.:|.  .....||.|||
plant   127 VYKY----KSGDGFVDGSDCSVCLSEFEENESLRLLPKCNHAFHLPCIDTWL--KSHSNCPLCRA 185

  Fly   411 EIKGTEQIVVDAFDPRKQHNRNVT----NGRQQQQEEDDTEDI-----------GDFN--IATSS 458
            .:.|..       :|.....:||:    |......:.....:|           |||:  :....
plant   186 FVTGVN-------NPTASVGQNVSVVVANQSNSAHQTGSVSEINLNLAGYESQTGDFDSVVVIED 243

  Fly   459 LHALSTSSTVAAEKHSPHTSPRLGRRSTTPSLMAVQNDLYAGGTPTLSLPSSSCSSIAAASTSSS 523
            |...|.:|...:|...|..     ||.|.      ..|         |||      |..:.:.:|
plant   244 LEIGSRNSDARSELQLPEE-----RRETK------DED---------SLP------IRRSVSLNS 282

  Fly   524 SSLASVATV----------AASTSSSQHQQ-----PQPSAPPASAVLSNGGGGG 562
            ..:.|:|.|          :....:||.::     ...:.||..|...:||..|
plant   283 GVVVSIADVLREIEDEEGESGGVGTSQRREEGEDGDGKTIPPTEANQRSGGVSG 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176	10/51 (20%)
		zf-C3HC4_3	367..415	CDD:290631	15/51 (29%)
		UBA_Cbl_like	834..873	CDD:270503
AT5G17600	NP_197262.1	zf-rbx1	122..184	CDD:289448	17/74 (23%)
AT5G17600	NP_197262.1	zf-RING_2	141..184	CDD:290367	12/44 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910