DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and AT3G58030

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_001190122.1	Gene:	AT3G58030 / 824972	AraportID:	AT3G58030	Length:	436	Species:	Arabidopsis thaliana

Alignment Length:	335	Identity:	67/335 - (20%)
Similarity:	116/335 - (34%)	Gaps:	128/335 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 GSTFQLCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQIV-------- 419
            |:.|. |.||.:..|:..:..||||.|.|||..|...|:.:.||.|:.|:  |.:.|
plant   134 GNFFD-CNICLDLSKEPVLTCCGHLYCWPCLYQWLQISDAKECPVCKGEV--TSKTVTPIYGRGN 195

  Fly   420 --------VDAFDPRKQHNRNVTNGRQ------------------QQQEEDDTEDIGDFNIATSS 458
                    :|...|.:.|.|.:.:.|.                  |.:.:.|:..:.||
plant   196 HKREIEESLDTKVPMRPHARRIESLRNTIQRSPFTIPMEEMIRRIQNRFDRDSTPVPDF------ 254

  Fly   459 LHALSTSSTVAAEKHSPHTSPRLGRRSTTPSLMAVQNDLYAGGTPTLSLPSSSCSSIAAASTS-- 521
                  |:..|:|:.:...:..|.|..|:..:.:.||.           .|::.::|.|||..
plant   255 ------SNREASERVNDRANSILNRLMTSRGVRSEQNQ-----------ASAAAAAIVAASEDID 302

  Fly   522 --------------------------SSSSLASVATVAASTSSSQ---------------HQQPQ 545
                                      .|..:|.::|..::.||::               ||:..
plant   303 LNPNIAPDLEGESNTRFHPLLIRRQLQSHRVARISTFTSALSSAERLVDAYFRTHPLGRNHQEQN 367

  Fly   546 PSAP----------PASAVLSNGGGGGGGGGASSSQKNTNRMSAPLIGSCVANSTYGQKLPQNCS 600
            ..||          ..:||::           |.||.:|    |..|.|...:::..::..:|.|
plant   368 HHAPVVVDDRDSFSSIAAVIN-----------SESQVDT----AVEIDSMALSTSSSRRRNENGS 417

  Fly   601 HSSTSSSSDN 610
            ..|...|:|:
plant   418 RVSDVDSADS 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176
		zf-C3HC4_3	367..415	CDD:290631	18/47 (38%)
		UBA_Cbl_like	834..873	CDD:270503
AT3G58030	NP_001190122.1	PLN03208	134..>226	CDD:178747	27/94 (29%)
AT3G58030	NP_001190122.1	RING-HC_AtRMA_like	137..180	CDD:319659	18/43 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910