Protein Alignment Cbl and Hrd1A

DIOPT Version :9

• Sequence 1: NP_648224.1
• Gene: Cbl / 38961
• FlyBaseID: FBgn0020224
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_188230.1
• Gene: Hrd1A / 820854
• AraportID: AT3G16090
• Length: 492
• Species: Arabidopsis thaliana
• Alignment Length: 285
• Identity: 61/285 - (21%)
• Similarity: 89/285 - (31%)
• Gaps: 104/285 - (36%)

  Fly   361 EMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQIVVDAFDP 425
            |:.::...|.||.|...:.:...||||....||.||.  ...|.||.|||.:...|
plant   284 ELTASDATCIICREEMTNAKKLICGHLFHVHCLRSWL--ERQQTCPTCRALVVPPE--------- 337

  Fly   426 RKQHNRNVTNGRQQQQEEDDTEDIGDFNIATSSLHALSTSSTVAAEKHSPHTSPRLGRRSTTPSL 490
                  |.|:....|:|                ||..|...|
plant   338 ------NATSAAPGQRE----------------LHQGSQQGT----------------------- 357

  Fly   491 MAVQNDLYAGGTPTLSLPSSSCSSIAAASTSSSSSLASVATVAASTSSSQHQQPQPSAPPASAVL 555
                                      ::|.:..|.::|.|.|:.::.|..|.:.|.:|..||..
plant   358 --------------------------SSSGNQGSEISSSAGVSNNSLSRHHARLQAAASAASVY- 395

  Fly   556 SNGGGGGGGGGASSSQKNTNRMSAPLIGSCVANSTYGQKLPQN-----CSH-----SSTSSSSDN 610
                    |........||...|:.:.|:...::...|.|||:     .||     |.|......
plant   396 --------GKSMVYPSANTVAWSSGVPGTEQVSTEPDQTLPQHNLPVENSHAYANMSETKLEEMR 452

  Fly   611 ASSSSSYAILQN-LH--DTGTPATA 632
            .|..:...||:| ||  :|..|.:|
plant   453 KSLETHLEILRNRLHFLETRKPESA 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176
		zf-C3HC4_3	367..415	CDD:290631	18/47 (38%)
		UBA_Cbl_like	834..873	CDD:270503
Hrd1A	NP_188230.1	HRD1	3..386	CDD:227568	35/183 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910