DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and AT2G42030

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_181733.1	Gene:	AT2G42030 / 818803	AraportID:	AT2G42030	Length:	425	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	83/320 - (25%)
Similarity:	121/320 - (37%)	Gaps:	77/320 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   346 EDHITVTQEQYELYCEMGS--TFQLCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFC 408
            ||:  ||:|:.::...:||  :|..|.||.:..||..:..||||.|..||..|...||.:.||.|
plant   118 EDN--VTEEKRDVEKSVGSDGSFFDCYICLDLSKDPVVTNCGHLYCWSCLYQWLQVSEAKECPVC 180

  Fly   409 RAEIKGTEQIVVDAFDPRKQHNRNVTNGRQQQQEEDDTEDIGDFNIAT--SSLHALSTSSTVAAE 471
            :.|:.      |....|        ..||..|:.|  :|::.:..|.:  .:....|..:|:...
plant   181 KGEVS------VKTVTP--------IYGRGIQKRE--SEEVSNTKIPSRPQARRTESLRTTLNRS 229

  Fly   472 KHSP-----HTSPRLGRRSTT------PSL---------MAVQN-----------------DLYA 499
            .|.|     |...||.|.|:|      |||         .|.:|                 ||..
plant   230 GHIPTEIFRHLQDRLERESSTGERRARPSLNRFMTSRGVRAEENQSSEALVEPSSDEINDIDLIL 294

  Fly   500 GGTPTLSLPSSSCSSIAAASTS----------SSSSLASVATVAAS---TSSSQHQQPQPSAPPA 551
            ...|.....:.:.||..|.:|.          ||.:|:|...:|.:   |.:....|.|.|:||.
plant   295 NNAPENEEENENLSSSRALATQRRWAQMYGRVSSFTLSSAERLADTYLITHALGRNQEQNSSPPV 359

  Fly   552 SAVLSNGGGGGGGGGASSSQKNTNRMSAPLIGSCVANSTYGQ-KLPQNCSHSSTSSSSDN 610
            .....:......|...|.||..|    |..|.|.:..||... :..:|.|..|...|:|:
plant   360 GVEDRDSFSSIVGVINSESQVET----AAEINSMLTVSTSSSVRRHENSSRVSDVDSADS 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176
		zf-C3HC4_3	367..415	CDD:290631	19/47 (40%)
		UBA_Cbl_like	834..873	CDD:270503
AT2G42030	NP_181733.1	PLN03208	124..>214	CDD:178747	31/105 (30%)
AT2G42030	NP_181733.1	RING-HC_AtRMA_like	139..182	CDD:319659	18/42 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910