DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and AT2G34990

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_001323608.1	Gene:	AT2G34990 / 818063	AraportID:	AT2G34990	Length:	324	Species:	Arabidopsis thaliana

Alignment Length:	252	Identity:	51/252 - (20%)
Similarity:	86/252 - (34%)	Gaps:	60/252 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 QAYNPDLSSAVQSPTE-------DHITVTQEQYELYCE-----MGSTFQLCKICA---ENDKDIR 380
            ::.||...|.|:|.|.       |...:......||.|     :|.....|.:|.   |:.:.:|
plant    68 ESINPFTDSDVESRTSITAVRGLDEAIINSFPTFLYSEVKERRIGIGGVECAVCICEFEDHETLR 132

  Fly   381 IEP-CGHLLCTPCLTSWQVDSEGQGCPFCRAEI---------KGTEQIVVDA-----FDPRKQHN 430
            :.| |.|:....|::.|.  |:...||.||.::         ...|..:|::     ||.....|
plant   133 LMPECCHVFHADCVSVWL--SDHSTCPLCRVDLCLQPGERSYLNPEPDLVESTNSHLFDGVTWTN 195

  Fly   431 RN-----------------VTNGRQQQQEEDDTEDIGDFNIAT----SSLHALSTSSTVAAEKHS 474
            ||                 :...|.........:.:.:.:..|    ..:....|..||.....|
plant   196 RNRPSRSWSTRLSQCRVSQILISRSHSTGHSVVQPLDNLDRFTLRLPEEVRRQLTKKTVDNVAFS 260

  Fly   475 PHTSPRLGRRSTTP----SLMAVQNDLYAGGTPTLSLPSSSCSSIAAASTSSSSSLA 527
            ...|.|.|.||.:.    |:.:.|..:::......   |:||...|.|.:..|..::
plant   261 QARSSRRGYRSRSAGSERSVFSYQRRMHSFSDCAW---STSCGGEAVAPSKDSRRIS 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176	2/8 (25%)
		zf-C3HC4_3	367..415	CDD:290631	14/60 (23%)
		UBA_Cbl_like	834..873	CDD:270503
AT2G34990	NP_001323608.1	RING-H2_PA-TM-RING	117..160	CDD:319368	12/44 (27%)
AT2G34990	NP_001323608.1	RING-H2 finger (C3H2C3-type)	118..159	CDD:319368	12/42 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910