DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and AT2G20030

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_179593.1	Gene:	AT2G20030 / 816522	AraportID:	AT2G20030	Length:	390	Species:	Arabidopsis thaliana

Alignment Length:	250	Identity:	47/250 - (18%)
Similarity:	80/250 - (32%)	Gaps:	75/250 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 CKICAENDKDIRI----EPCGHLLCTPCLTSWQVDSEGQGCPFCRAEI-----------KGTEQI 418
            |.:|....:|:.|    ..|.|.....|:..|.  .:...||.||..:           ..|...
plant   124 CSVCLSKFEDVEILRLLPKCRHAFHIGCIDQWL--EQHATCPLCRNRVNIEDDLSVLGNSSTSLR 186

  Fly   419 VVDAFDPRKQHNR--------NVTNGRQQQ-------------QEEDDTEDIGDFNIATSSLHAL 462
            :::..:.|::.:|        ..||....:             .|.:..|:|.:..:.....|.:
plant   187 ILNQSETREEDSRLEIYIEREEGTNDGSSRFSSFRKILKKSLLLEREGNENIDEKKLMHKFNHRI 251

  Fly   463 STSSTVAAEKHSPHTSPRLGRRSTTPSLMAVQNDLYAGGTPTLSLPSSSCSSIAAASTSSSSSL- 526
            ..|..|...:.|..||..| ...|:..|.:|.:|.:           ||...:...:......:
plant   252 VVSDAVFKNRWSNITSSDL-TFLTSEMLNSVSSDRF-----------SSVDRVHRGNLRDKEDME 304

  Fly   527 ----------ASVATVAASTSSSQHQQPQPSAPPASAVLSNGGGGGGGGGASSSQ 571
                      :|..||:..|:.|:.:          ||    ||...|..||:||
plant   305 MKRMLIKHKDSSRRTVSEITTVSREK----------AV----GGSYRGSTASTSQ 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176
		zf-C3HC4_3	367..415	CDD:290631	12/60 (20%)
		UBA_Cbl_like	834..873	CDD:270503
AT2G20030	NP_179593.1	RAD18	114..>202	CDD:227719	15/79 (19%)
AT2G20030	NP_179593.1	RING-H2_PA-TM-RING	123..166	CDD:319368	10/43 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910