DRSC - DRSC Integrative Ortholog Prediction Tool

Protein Alignment Cbl and BRCA1

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_009231.2	Gene:	BRCA1 / 672	HGNCID:	1100	Length:	1884	Species:	Homo sapiens

Alignment Length:		Identity:	/ - (0%)
Similarity:	/ - (0%)	Gaps:	/ - (0%)

- Green bases have known domain annotations that are detailed below.

Gene	Sequence	Domain	Region	External ID
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176
		zf-C3HC4_3	367..415	CDD:290631
		UBA_Cbl_like	834..873	CDD:270503
BRCA1	NP_009231.2	RING	23..68	CDD:238093
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..270
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..338
		BRCT_assoc	345..507	CDD:289581
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	534..570
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	654..709
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1181..1216
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1322..1387
		Interaction with PALB2. /evidence=ECO:0000269\|PubMed:19369211	1397..1424
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1586..1617
		BRCT	1671..1745	CDD:237994
		BRCT	1779..1863	CDD:214602
Blue background indicates that the domain is not in the aligned region.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910