DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cbl and Rnf5

DIOPT Version :9

Sequence 1:NP_648224.1 Gene:Cbl / 38961 FlyBaseID:FBgn0020224 Length:878 Species:Drosophila melanogaster
Sequence 2:NP_062276.1 Gene:Rnf5 / 54197 MGIID:1860076 Length:180 Species:Mus musculus


Alignment Length:82 Identity:27/82 - (32%)
Similarity:40/82 - (48%) Gaps:16/82 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   364 STFQLCKICAENDKDIRIEPCGHLLCTPCLTSW-QVDSEGQGCPFCRAEIKGTEQIVVDAFDPRK 427
            :||: |.||.|..::..:..||||.|.|||..| :...:.|.||.|:|.|  :.:.||..:    
Mouse    23 ATFE-CNICLETAREAVVSVCGHLYCWPCLHQWLETRPDRQECPVCKAGI--SREKVVPLY---- 80

  Fly   428 QHNRNVTNGRQQQQEED 444
                    ||..|:.:|
Mouse    81 --------GRGSQKPQD 89

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CblNP_648224.1 Cbl_N 42..163 CDD:280432
Cbl_N2 167..250 CDD:280857
SH2_Cbl-b_TKB 244..340 CDD:198176
zf-C3HC4_3 367..415 CDD:290631 19/48 (40%)
UBA_Cbl_like 834..873 CDD:270503
Rnf5NP_062276.1 PLN03208 25..>117 CDD:178747 26/80 (33%)
RING-HC_RNF5 25..70 CDD:319657 18/45 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 79..110 4/23 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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