DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and SPBC14F5.10c

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_596736.1	Gene:	SPBC14F5.10c / 2539750	PomBaseID:	SPBC14F5.10c	Length:	486	Species:	Schizosaccharomyces pombe

Alignment Length:	149	Identity:	37/149 - (24%)
Similarity:	57/149 - (38%)	Gaps:	36/149 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 YPDGQAYNPDLSSAVQS-----PTEDHITVTQEQYEL----YCEMGSTFQ-------LCKICAEN 375
            :.|..:.:|..:||:..     ||..::..:...||.    :..|....|       .|:||...
pombe   111 HDDCLSSSPPCTSALTEITLLPPTFHNLIPSSSSYETAVAEFLHMEDLLQENVSRELECQICFGM 175

  Fly   376 DKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQIVVDAFDPRKQHNRNVTN----- 435
            ..|..:.||||..|.|||  .|..::...||.||.   |....||  .:..|.|  ::|.
pombe   176 LYDPVVSPCGHTFCGPCL--MQALTQSPQCPTCRF---GLPSPVV--LEHAKSH--SITTFLRDF 231

  Fly   436 ------GRQQQQEEDDTED 448
                  .||:..||:..::
pombe   232 YPDNWLERQKSWEEEKEQE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176	2/12 (17%)
		zf-C3HC4_3	367..415	CDD:290631	18/54 (33%)
		UBA_Cbl_like	834..873	CDD:270503
SPBC14F5.10c	NP_596736.1	RING	168..207	CDD:238093	15/40 (38%)
		LON_substr_bdg	252..470	CDD:280370
		LON	259..485	CDD:225362
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910