DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbl and ftr97

DIOPT Version :9

Sequence 1:	NP_648224.1	Gene:	Cbl / 38961	FlyBaseID:	FBgn0020224	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	XP_002665768.3	Gene:	ftr97 / 100150342	ZFINID:	ZDB-GENE-061026-1	Length:	794	Species:	Danio rerio

Alignment Length:	162	Identity:	35/162 - (21%)
Similarity:	50/162 - (30%)	Gaps:	47/162 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 DHITVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTS-WQVDSEG-QGCPFCR 409
            ||     :||.           |.:|.:..:|....||||..|..|:.. |..|.:. ..||.||
Zfish     7 DH-----DQYS-----------CSVCLDLLRDPVTIPCGHSYCMSCINECWNKDQKAPYKCPQCR 55

  Fly   410 AEIKGTEQIVVDAFDPRKQHNRNVTNGRQQQQ---EEDDTEDIGDFNIAT-----SSLHALSTSS 466
                       ..|..:...||:.......::   :|......|...||.     .|:.|:.:..
Zfish    56 -----------HTFSSKPPLNRSTVLAELMEKLRAQESPQSPAGPGEIACDFCVGESIKAVKSCM 109

  Fly   467 TVAAEKHSPHTSPR----------LGRRSTTP 488
            ...|.....|..|.          |.:.||.|
Zfish   110 ECRASYCELHVQPHYNVPALRKHVLVKASTIP 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbl	NP_648224.1	Cbl_N	42..163	CDD:280432
		Cbl_N2	167..250	CDD:280857
		SH2_Cbl-b_TKB	244..340	CDD:198176
		zf-C3HC4_3	367..415	CDD:290631	15/49 (31%)
		UBA_Cbl_like	834..873	CDD:270503
ftr97	XP_002665768.3	zf-C3HC4_4	13..54	CDD:291880	13/40 (33%)
		zf-B_box	138..177	CDD:279037	3/4 (75%)
		DUF4200	183..299	CDD:290574
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910