DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cbl and cop1

DIOPT Version :9

Sequence 1:NP_648224.1 Gene:Cbl / 38961 FlyBaseID:FBgn0020224 Length:878 Species:Drosophila melanogaster
Sequence 2:NP_001083011.1 Gene:cop1 / 100037391 ZFINID:ZDB-GENE-070410-134 Length:694 Species:Danio rerio


Alignment Length:229 Identity:51/229 - (22%)
Similarity:84/229 - (36%) Gaps:37/229 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   368 LCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQ-----IVVDAFDPRK 427
            :|.||.|..::..:..|||..|..|:.....||  ..||.|...|...:|     :|.:....:|
Zfish    97 VCPICFEMIEEAHMTKCGHSFCYKCIRQSLEDS--NRCPKCNYIIDNVDQLYPNFLVNELILKQK 159

  Fly   428 QHN------RNVTNGRQQQQEED----DTEDIGDFNIATSSLHALSTSSTVAAEKHSPHTSPRL- 481
            |.:      |:..||.:.|..:|    |.|::...|:.....:.|.....:.||..:......: 
Zfish   160 QRSEEKRLKRDHPNGTKWQVFQDVLGADQENMDLANVNYILEYLLQKKKQLEAESQAAQRQILME 224

  Fly   482 ----GRRSTTPSLMAVQNDL--YAGGTPTLSLPSSSCSSIAAASTSSSSSLASVATVAASTSSSQ 540
                .||:....|..:|.:|  .......:...|...|.|:....:|.|::..|...:.:.|||.
Zfish   225 FLKEARRNKREQLEQLQKELNFLEEDIKRVEEMSGMYSPISDMDCNSDSTVPQVEAPSPAPSSSI 289

  Fly   541 HQQPQPSAPPASAVLSNGGGGGGGGGASSSQKNT 574
            ....:...||.             ||.|.|::.|
Zfish   290 IDPSEYIQPPF-------------GGNSQSKRQT 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CblNP_648224.1 Cbl_N 42..163 CDD:280432
Cbl_N2 167..250 CDD:280857
SH2_Cbl-b_TKB 244..340 CDD:198176
zf-C3HC4_3 367..415 CDD:290631 15/46 (33%)
UBA_Cbl_like 834..873 CDD:270503
cop1NP_001083011.1 zf-C3HC4 98..135 CDD:278524 13/38 (34%)
NAM-associated <200..260 CDD:291001 9/59 (15%)
WD40 384..690 CDD:238121
WD40 repeat 387..418 CDD:293791
WD40 repeat 436..473 CDD:293791
WD40 repeat 480..516 CDD:293791
WD40 repeat 521..559 CDD:293791
WD40 repeat 565..600 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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