Protein Alignment Exo70 and Exoc7

DIOPT Version :10

• Sequence 1: NP_648222.3
• Gene: Exo70 / 38959
• FlyBaseID: FBgn0266667
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: XP_063125893.1
• Gene: Exoc7 / 64632
• RGDID: 620236
• Length: 740
• Species: Rattus norvegicus
• Alignment Length: 747
• Identity: 238/747 - (31%)
• Similarity: 388/747 - (51%)
• Gaps: 81/747 - (10%)

  Fly     9 QAHNKLEKEATNLALLKDRVDKYHDLSTQMSSILTIFEKRLGNLEQTILPVYQETEQLQKRQQNL 73
            :..:||::|...|:.::|.::|...|:..|.|||:.||.||..||.:|:||:::||.||:.|:|:
  Rat    13 EIEDKLKQEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENV 77

  Fly    74 EATLNCLESVLSHYDVSQEVCQLIHQGPVEGNISVFLDALAKLRDANDYFRHNNSQSVELENVTS 138
            |.||:||:.|:|:|.|:.:..::|.:||. |.:..:|.::||::.|.:||:.|:..|.||..|..
  Rat    78 EKTLSCLDHVISYYHVASDTEKIIREGPT-GRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKL 141

  Fly   139 LFNTGCEGLSQHYSMLLKKHSAPLKPVELLDLIYIEDD-SSDEYTSFRQLSQTTREELYTISHWL 202
            ||..|.|.|...:..|:.:||..:.||.:||||..:|: ...|......|.::..:::..||.||
  Rat   142 LFERGKESLESEFRSLMTRHSKVISPVLVLDLISADDELEVQEDVVLEHLPESVLQDVIRISRWL 206

  Fly   203 EQNLR--EYTNIYATERGEVVLRSLQLLKDH-QKSNSWGHEALRPR--HSGRQTEPKKT-----T 257
            .:..|  ::.|:|...|...:.||::.||:| :||:|.......|.  :..:.|..||.     |
  Rat   207 VEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGT 271

  Fly   258 SARLQQIFE---------KK--ANKLYLRATQTIE--------QSTG------------------ 285
            ..:.|.:.:         ||  :|.:.|.....|:        |..|
  Rat   272 IRKAQNLLKQYSQHGLDGKKGGSNLIPLEGNHPIKGFVPIPKGQLPGPWINAACVCVADILLGHE 336

  Fly   286 --FSIKKAS-----SHSDHLTSEDLMDGDQELDKYLVMLLGLQRLLNWERAIMIDIIPQSKHNEV 343
              |.:|..|     .|......:|::  |.|.|.|:..:....||...|..:::.|||:....:.
  Rat   337 HDFRVKHLSEALNDKHGPLAGRDDML--DVETDAYIHCVSAFVRLAQSEYQLLMGIIPEHHQKKT 399

  Fly   344 FATLAYNAIDLVVKDAEAITQRILRCISRKEWTSALGIFSALKRVILLQPDIDRTYD---PAQRE 405
            |.:|..:|:|.::.:.|.|.....:.|.|.::::.|.:|..|:.:...:|:.|:...   .:.:.
  Rat   400 FDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKN 464

  Fly   406 QLKKVLKKLQHTGAKALEHFLDVVKGESSTNIVGQSNVPKDATVHELTSNTIWFIEHLYDHFDVI 470
            :|..::..::..||||||.|.|.:|.:...    :.|:|||.||||||||.|.|::.|.|..:..
  Rat   465 KLPGLITSMETIGAKALEDFADNIKNDPDK----EYNMPKDGTVHELTSNAILFLQQLLDFQETA 525

  Fly   471 GSILAQDVLYS--TQLDTILMKKALPVEERNKALLAIYIKKALAELNLSIMNKCEQYNDQATKHL 533
            |::||.....|  |..::          |.:|.||:.||.|.|..|.|::::|.:.|.|.|...:
  Rat   526 GAMLASQETSSSATSYNS----------EFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAI 580

  Fly   534 FRLNNIHYILKSLQRSNLIDLVTLAEPECEHSYMEMIRELKASYQKTWSKMLVGIYSLDE-LPKP 597
            |..||.:||||||::|.||.||.:.:...|.||.|.|.:...:||::|.|  |..|..:: ||..
  Rat   581 FLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLK--VTDYIAEKNLPVF 643

  Fly   598 VAG-KVKDKDRSVLKERFSNFNKDFEEACKIQRGISIPDVILREGIKRDNVEHILPIYNRFYEIY 661
            ..| |::||:|.::||||..||...||.||||:..:|||...|:.|::.....:...|..|...|
  Rat   644 QPGVKLRDKERQMIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKSIVKETYGAFLHRY 708

  Fly   662 SGVHFSKNPDKYVKYRQHEINAMLSKLFDDSA 693
            |.|.|:|||:||:|||..::..|:.:|||.||
  Rat   709 SSVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exo70	NP_648222.3	Exo70	315..686	CDD:460798	128/377 (34%)
Exoc7	XP_063125893.1	None