Protein Alignment Exo70 and Exoc7

DIOPT Version :9

• Sequence 1: NP_648222.3
• Gene: Exo70 / 38959
• FlyBaseID: FBgn0266667
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_073182.1
• Gene: Exoc7 / 64632
• RGDID: 620236
• Length: 653
• Species: Rattus norvegicus
• Alignment Length: 698
• Identity: 227/698 - (32%)
• Similarity: 371/698 - (53%)
• Gaps: 70/698 - (10%)

  Fly     9 QAHNKLEKEATNLALLKDRVDKYHDLSTQMSSILTIFEKRLGNLEQTILPVYQETEQLQKRQQNL 73
            :..:||::|...|:.::|.::|...|:..|.|||:.||.||..||.:|:||:::||.||:.|:|:
  Rat    13 EIEDKLKQEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENV 77

  Fly    74 EATLNCLESVLSHYDVSQEVCQLIHQGPVEGNISVFLDALAKLRDANDYFRHNNSQSVELENVTS 138
            |.||:||:.|:|:|.|:.:..::|.:||. |.:..:|.::||::.|.:||:.|:..|.||..|..
  Rat    78 EKTLSCLDHVISYYHVASDTEKIIREGPT-GRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKL 141

  Fly   139 LFNTGCEGLSQHYSMLLKKHSAPLKPVELLDLIYIEDD-SSDEYTSFRQLSQTTREELYTISHWL 202
            ||..|.|.|...:..|:.:||..:.||.:||||..:|: ...|......|.::..:::..||.||
  Rat   142 LFERGKESLESEFRSLMTRHSKVISPVLVLDLISADDELEVQEDVVLEHLPESVLQDVIRISRWL 206

  Fly   203 EQNLR--EYTNIYATERGEVVLRSLQLLKDH-QKSNSWGHEALRPR--HSGRQTEPKKTTSARLQ 262
            .:..|  ::.|:|...|...:.||::.||:| :||:|.......|.  :..:.|..||
  Rat   207 VEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKK------- 264

  Fly   263 QIFEKKANKLYLRATQTIEQSTGFSIKKASSHSDHLTSEDLMDGDQELDKYLVMLLGLQRLLNWE 327
                                    .||:..       .:|::  |.|.|.|:..:....||...|
  Rat   265 ------------------------PIKRPG-------RDDML--DVETDAYIHCVSAFVRLAQSE 296

  Fly   328 RAIMIDIIPQSKHNEVFATLAYNAIDLVVKDAEAITQRILRCISRKEWTSALGIFSALKRVILLQ 392
            ..:::.|||:....:.|.:|..:|:|.::.:.|.|.....:.|.|.::::.|.:|..|:.:...:
  Rat   297 YQLLMGIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTK 361

  Fly   393 PDIDRTYD---PAQREQLKKVLKKLQHTGAKALEHFLDVVKGESSTNIVGQSNVPKDATVHELTS 454
            |:.|:...   .:.:.:|..::..::..||||||.|.|.:|.:...    :.|:|||.|||||||
  Rat   362 PEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDK----EYNMPKDGTVHELTS 422

  Fly   455 NTIWFIEHLYDHFDVIGSILAQDVLYS--TQLDTILMKKALPVEERNKALLAIYIKKALAELNLS 517
            |.|.|::.|.|..:..|::||.....|  |..::          |.:|.||:.||.|.|..|.|:
  Rat   423 NAILFLQQLLDFQETAGAMLASQETSSSATSYNS----------EFSKRLLSTYICKVLGNLQLN 477

  Fly   518 IMNKCEQYNDQATKHLFRLNNIHYILKSLQRSNLIDLVTLAEPECEHSYMEMIRELKASYQKTWS 582
            :::|.:.|.|.|...:|..||.:||||||::|.||.||.:.:...|.||.|.|.:...:||::|.
  Rat   478 LLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWL 542

  Fly   583 KMLVGIYSLDE-LPKPVAG-KVKDKDRSVLKERFSNFNKDFEEACKIQRGISIPDVILREGIKRD 645
            |  |..|..:: ||....| |::||:|.::||||..||...||.||||:..:|||...|:.|::.
  Rat   543 K--VTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQA 605

  Fly   646 NVEHILPIYNRFYEIYSGVHFSKNPDKYVKYRQHEINAMLSKLFDDSA 693
            ....:...|..|...||.|.|:|||:||:|||..::..|:.:|||.||
  Rat   606 QKSIVKETYGAFLHRYSSVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exo70	NP_648222.3	Exo70	315..686	CDD:397277	128/377 (34%)
Exoc7	NP_073182.1	SEC8 and ARHQ binding. /evidence=ECO:0000250	1..384		114/411 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..272		9/71 (13%)
		Exo70	288..647	CDD:281124	128/374 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339136
Domainoid	1	1.000	210	1.000	Domainoid score	I2734
eggNOG	1	0.900	-	-		E1_KOG2344
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	349	1.000	Inparanoid score	I2219
OMA	1	1.010	-	-		QHG56212
OrthoDB	1	1.010	-	-		D186707at33208
OrthoFinder	1	1.000	-	-		FOG0000506
OrthoInspector	1	1.000	-	-		oto98372
orthoMCL	1	0.900	-	-		OOG6_102697
Panther	1	1.100	-	-	LDO	PTHR12542
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X7127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810