Protein Alignment Exo70 and exo70

DIOPT Version :9

• Sequence 1: NP_648222.3
• Gene: Exo70 / 38959
• FlyBaseID: FBgn0266667
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_595170.2
• Gene: exo70 / 2540127
• PomBaseID: SPBC106.20
• Length: 615
• Species: Schizosaccharomyces pombe
• Alignment Length: 739
• Identity: 152/739 - (20%)
• Similarity: 268/739 - (36%)
• Gaps: 240/739 - (32%)

  Fly    39 SSILTIFEKRLGNLEQTILPVYQETEQLQKRQQNLEATLNCLES---VLSHYDVSQ---EVCQLI 97
            |:||...:|||..||.:...:..:.....:...|:..||..:||   :.||..|.|   :.||.:
pombe    31 SNILLSMDKRLSGLEASAGILRDDVTNYNRVSSNIYDTLKEMESLQVIHSHLPVLQKGLQECQNL 95

  Fly    98 HQGPVEGNISVFLDALAKLRDANDY---------FRHNNSQSVELENVTSLFNTGCEGLSQHYSM 153
            ::. |..|:...:|.|..|  |.||         |...:.|.||:     :.:.||:.|......
pombe    96 NKS-VSQNLKSVMDILKSL--AEDYTSLEGSPLQFASKSQQKVEM-----MLSEGCQILGALCYN 152

  Fly   154 LLKKHSAPL--KPVELLDLIY---IEDDSSDEYTSFRQLSQTTREELYTISHWLEQNLREYTNIY 213
            :|:.::|..  |...||||..   ..::|..::...  :.|...:.|:.:|     ...:.:|||
pombe   153 ILETYAASSLNKASTLLDLSIPWSFPNESLQQFIGL--IQQFDADVLFPVS-----CSSDISNIY 210

  Fly   214 ATERGEVVLRSLQLLKDHQKSNSWGHEALRPRHSGRQTEPKKTTSARLQQIFEKKANKLYLRATQ 278
            ...:||.|::.|.                             ..|.|..:|   |.|
pombe   211 IKIKGECVVKLLH-----------------------------AVSMRTDEI---KLN-------- 235

  Fly   279 TIEQSTGFSIKKASSHSDHLTSEDLMDGDQELDKYLVMLLGLQRLLNWERAIMIDIIPQSKHNEV 343
              |.|..|...|          ||:.          :.|:.|.|||....:.::.:..|.....:
pombe   236 --EGSVNFVTGK----------EDVS----------INLVALSRLLPAVASELLLLFDQVTAKAL 278

  Fly   344 FATLAYNAIDLVVK------------------------DAEAITQRILRCISRKEWTSALGIFSA 384
            :..:...||:.|..                        |...:|::.:..:...|..|.||..:.
pombe   279 YPKIVKPAINTVTNATRQLEGVYEKRGAAENFVLLSLIDCIVVTRQNMNNLMPFEDASFLGFVNG 343

  Fly   385 LKRVI--LLQPDIDRTYD---------PAQREQLKKV-------LKKL-QHTGAKALEHFLDVVK 430
            :.|.:  :|...|.|.|:         |...:::.::       |.:| :|..|..|.
pombe   344 VGREMEKILISSISRLYNGTCHNNKTVPLTTDRVSEMTHGIMSFLNELAEHENASYLL------- 401

  Fly   431 GESSTNIVGQSNVPKD----ATVHELTSNTIWFIEHLYDHFDVIGSILAQDVLYSTQLDTILMKK 491
             ||..|...:..:..|    .:|.::|.|.:         .|.:.|.|......:..:|||..|.
pombe   402 -ESIGNWGWRHEINADLSPARSVQDITRNYV---------MDCMDSYLTSVQTAAQAVDTIGWKM 456

  Fly   492 ALPVEERNKALLAIYIKKALAELNLSIM--NKCEQYNDQATKHLFRLNNIHYILKSLQRSNL--I 552
            .:.:                  ||:|:.  .||                    |:|...|.|  :
pombe   457 GVML------------------LNISVYFEAKC--------------------LESKIASFLQDV 483

  Fly   553 DLVTLAEPECEHS--YMEMIRE-----LKASYQKTWSKMLVGIYSLDELPKPVAGKVKDKDRSVL 610
            ||..|.:...::|  |||:.|:     |.::|.|:.:|                ..:..|:|.:.
pombe   484 DLEKLGDRSQKYSTMYMEVWRQCSQNMLDSTYTKSQNK----------------STMSAKEREIT 532

  Fly   611 KERFSNFNKD-------FEEACKIQRGISIPDVILREGIKRDNVEHILPIYNRFYEIYSGVHFSK 668
            ||:|.|||:.       ..|:.:.:.|::   ..|.:.:|:.    :||:|.|||:.|....|:|
pombe   533 KEKFRNFNEQVTSVVQVHRESVRFETGVA---TFLLQEVKKT----VLPLYQRFYDKYINSDFTK 590

  Fly   669 NPDKYVKYRQHEINAMLSKLFDDS 692
            |.|||:|:.:.::::.::..|..|
pombe   591 NKDKYIKFTKADLDSFITSAFAPS 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exo70	NP_648222.3	Exo70	315..686	CDD:397277	87/435 (20%)
exo70	NP_595170.2	Exo70	253..609	CDD:281124	86/433 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2344
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I1716
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000506
OrthoInspector	1	1.000	-	-		oto101919
orthoMCL	1	0.900	-	-		OOG6_102697
Panther	1	1.100	-	-	LDO	PTHR12542
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3620
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.980