Protein Alignment Exo70 and exoc-7

DIOPT Version :9

• Sequence 1: NP_648222.3
• Gene: Exo70 / 38959
• FlyBaseID: FBgn0266667
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_491337.1
• Gene: exoc-7 / 172023
• WormBaseID: WBGene00016606
• Length: 630
• Species: Caenorhabditis elegans
• Alignment Length: 694
• Identity: 149/694 - (21%)
• Similarity: 282/694 - (40%)
• Gaps: 115/694 - (16%)

  Fly    13 KLEKEATNLALLKDRVDKYHDLSTQMSSILTIFEKRLGNLEQTILPVYQETEQLQKRQQNLEATL 77
            ||.:|...|...:..:.|...:...:..::..|::||.:||:.:||::....:|||:|.|::..:
 Worm    35 KLAQEEEWLQNFQKNIAKSAQIRQGIEQVVEKFDQRLSSLEKNVLPMHISNGKLQKKQHNIQRLI 99

  Fly    78 NCLESVLSHYDVSQEVCQLIHQGPVEGNISVFLDALAKLRDANDYFR-HNNSQSVELENVTSLFN 141
            |.:::.|..|..:..|...|:.|....::..:|:.:..|:.|..:|. |.|.:| :.:|:....:
 Worm   100 NTIDATLQFYGKTSTVENAINSGNPSVDLDPYLENMESLQQAIIFFETHPNYRS-QTDNMRITLD 163

  Fly   142 TGCEGLSQHYSMLLKKHSAPLKPVELLDLIYIEDDSSDEYTSFRQLSQTTREELYTISHWLEQNL 206
            ||...|.:.|...|.|:|..:.|..     :::::.:...:..:.:  |..|.:..|..||.:..
 Worm   164 TGYTMLEKAYKNFLLKNSITVDPAP-----FVKNELTPRLSEIKIM--TDEEPIIKIGVWLLKQP 221

  Fly   207 R---EYTNIYATERGEVVLRSLQLLKDHQKSNSWGHEALRPRHSGRQTEPKKTTSARLQQIFEKK 268
            |   .:...|:..||..:|::::.:.:.|||            |...:..|.:|:.|
 Worm   222 RVPNNFLGYYSEIRGAQILKNIKSIAEAQKS------------SQLASRSKLSTAVR-------- 266

  Fly   269 ANKLYLRATQTIEQSTGFSIKKASSHSDHLTSEDLMDGDQELDKYLVMLLGLQRLLNWERAIMID 333
                     :.:::|....:              |:|    ||....|...|..||..|..:|:.
 Worm   267 ---------KPVQRSEKVDV--------------LID----LDACHAMCSALLSLLELEEKLMVK 304

  Fly   334 IIPQ-SKHNEVFATLAYNAIDLVVKDAEAITQRILRCISRKEWTSALGIFSALKRVILLQPDIDR 397
            .||. ||..:||..|....:...|..    ||::   ::.|:    :||...|..:.||..:..|
 Worm   305 AIPDTSKRAQVFRELVSRPLAYAVVQ----TQKV---VNEKD----IGIVPLLPLLHLLSQNYAR 358

  Fly   398 TYDPAQRE----QLKKVLKKLQHTGAKALEHFLDVVK--GESSTNIVGQSNVPKDATVHELTSNT 456
            .::.|...    |...::::||   .|...:..:|::  .|.:|..     ||.|..||..|::|
 Worm   359 FHNLATNSIGDVQFDSLMRQLQ---VKCSSYVNEVIENLNEDTTKF-----VPPDGNVHPTTAST 415

  Fly   457 IWFIEHLYDHFDVIGSILAQDVLYSTQLDTILMKKALPVEERNKALLAIYIKKALAELNLSIMNK 521
            :.|:..|..|...:    .|.||..|          .|.......||.....:.|:.|...:..|
 Worm   416 LNFLSSLTAHRVTV----TQHVLALT----------APQGSNTNLLLPKLFARILSALGSMLKKK 466

  Fly   522 CEQYNDQATKHLFRLNNIHYILKSL--QRSNLIDLVTLAEPECEHSYMEMIRELKASYQKTWSKM 584
            ...|:|.....:|.|||.:||.|:|  ::..|:..:|.........|.|.|......|.|:|:.:
 Worm   467 ANLYDDPTLATIFLLNNYNYIAKTLADEQDGLLPAITEMNSNILSFYHEEIATCTNEYLKSWNGI 531

  Fly   585 LVGIYSLDELPKPVAGKVKDKDRSVLKERFSNFNKDFEEACKIQRGISIPDVILREGIKRDNVEH 649
            ...:.|:|.:         .:|:.:.|:..|.|.:||::....|....|.|..:...::......
 Worm   532 ASILKSVDRI---------GEDKQMAKQIMSTFVRDFDQVLAQQMDYCISDPKISANVQTQVKSR 587

  Fly   650 ILPIYNRFYEIYSGVH-FSKNPDKYVKYRQHEINAMLSKLFDDS 692
            |...|::..:....:| |.:.    :||.::.....:..||..:
 Worm   588 IWKNYSQLLDTCQRLHVFPQG----IKYTENTFEMAIRNLFSSA 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exo70	NP_648222.3	Exo70	315..686	CDD:397277	86/380 (23%)
exoc-7	NP_491337.1	Exo70	<371..620	CDD:281124	62/283 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158566
Domainoid	1	1.000	69	1.000	Domainoid score	I6323
eggNOG	1	0.900	-	-		E1_KOG2344
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3342
Isobase	1	0.950	-	0	Normalized mean entropy	S4857
OMA	1	1.010	-	-		QHG56212
OrthoDB	1	1.010	-	-		D186707at33208
OrthoFinder	1	1.000	-	-		FOG0000506
OrthoInspector	1	1.000	-	-		oto19984
orthoMCL	1	0.900	-	-		OOG6_102697
Panther	1	1.100	-	-	LDO	PTHR12542
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3620
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.750