Protein Alignment Oseg1 and Oseg1

DIOPT Version :10

• Sequence 1: NP_648221.3
• Gene: Oseg1 / 38957
• FlyBaseID: FBgn0265102
• Length: 1169
• Species: Drosophila melanogaster
• Sequence 2: XP_316573.3
• Gene: Oseg1 / 1277134
• VectorBaseID: AGAMI1_007399
• Length: 1170
• Species: Anopheles gambiae
• Alignment Length: 1172
• Identity: 779/1172 - (66%)
• Similarity: 972/1172 - (82%)
• Gaps: 9/1172 - (0%)

  Fly     1 MRGVLKWLERIEFPNSKDNEISVHNVCYAPDGSQLVVAAGDRLLIYDPNDGSLLNTLKAHKDTVN 65
            ||.:.||:|:|...:.|.:..|:|::||.|:|.||||||||::|:|||.||:|:|:||.|||||.
Mosquito     1 MRAIPKWVEKIHDSSDKSDVASIHSLCYHPEGLQLVVAAGDKVLVYDPIDGNLINSLKGHKDTVY 65

  Fly    66 CVAYSRDGKRFASGASDKMVIVWSPQLEGLLKYSHGDSIQCMSFNPVSHHLASCSLSDFAFWSAD 130
            ||||:||||:||||::||.||:|:.:|||||||||.|||||::|||:||.||||::|||:|||::
Mosquito    66 CVAYARDGKKFASGSADKTVIIWTQKLEGLLKYSHNDSIQCLAFNPISHQLASCAVSDFSFWSSE 130

  Fly   131 QKAVQKYKISARVNGCSWTNDGQYLILGLANGTISIRNKLGEEKGRIDRPGGPNSNVFSVQCCPA 195
            ||||||||..||:|.|:|||||||:.|||||||||||||.||||.:|:|||||||.:|.:...|.
Mosquito   131 QKAVQKYKSVARINACAWTNDGQYIALGLANGTISIRNKAGEEKIKIERPGGPNSPIFGLAWNPP 195

  Fly   196 SGPGSVDTIGVVDWSQTLSFHTLSGQMIGKERTLGFDPLCLQYFPNGEFCLVGGCTGGLHFFTRE 260
            :..||.|.:.|:||:|||||::|.||||||||...||||||.:||||||.:|.||...|..|||:
Mosquito   196 ATSGSSDILCVIDWAQTLSFYSLGGQMIGKERNFAFDPLCLTFFPNGEFLIVAGCNKALQLFTRD 260

  Fly   261 GIRLGTLGDTFDTWIWTVALHPNGQSYTIGCQDGTLACFNIASSTVHALYRERYAFRENMCDVII 325
            |||||.||:..::|||:.|:||.|....:|||||||.|:.:|.:|||||||||||||||||||||
Mosquito   261 GIRLGLLGEQHESWIWSAAVHPAGNCVVVGCQDGTLGCYTLAFNTVHALYRERYAFRENMCDVII 325

  Fly   326 QHLISGQKVRIKCRDLVQKIAIYRNRLAVQLPERVVLYELSSGEDQPMHYKVREKIQQKFDCSLL 390
            |||:|||||||||||||.||||||||||||||||||||||||.|:|||||||:|||.:|||||||
Mosquito   326 QHLVSGQKVRIKCRDLVHKIAIYRNRLAVQLPERVVLYELSSAENQPMHYKVKEKIAKKFDCSLL 390

  Fly   391 VVCGRHIVLCQEKRLQCLDFMGVLQREWIMDSFIRYIKVTGGPVGREGLMVGLKNGQVFRIFLNN 455
            |||.:|:||||||:||.|||.|||||||:||||||||||||||.|||||::|||:|||:||||:|
Mosquito   391 VVCAQHLVLCQEKKLQSLDFNGVLQREWMMDSFIRYIKVTGGPAGREGLLLGLKSGQVWRIFLDN 455

  Fly   456 SLPLLITTAVSAVRCLDINSKRSKIAVVDDVGRLVVRDVINDTILYQDTGVNSVTWNTHLDSMLC 520
            |||:|:||.:|:|||||:|:.|:|:|||||.|||||||:|.||:|||||.||||.|||||:||||
Mosquito   456 SLPILVTTVLSSVRCLDLNASRTKLAVVDDAGRLVVRDLIADTMLYQDTSVNSVAWNTHLESMLC 520

  Fly   521 YTHTTGGLSVRVGNLPPRAPQNMHGVVVGLCGATAFCLRGNIMHNTPLALGSTMWQFIEAGLFDE 585
            |:|||||||||||:||||:||.|.|||||||||||||||||:|.|.|||||:|||||:|||||::
Mosquito   521 YSHTTGGLSVRVGSLPPRSPQTMLGVVVGLCGATAFCLRGNVMSNVPLALGATMWQFVEAGLFED 585

  Fly   586 AYQVACLGVTTSDWEGLAQSALEALHINIARDAYVKVRNLPWLKLIGELRDQQQRSAVPKEVLLA 650
            |||||||||..||||||||:||:||:..:||||||||||||||:|||:|:::|:|....||||||
Mosquito   586 AYQVACLGVPMSDWEGLAQAALDALNYQVARDAYVKVRNLPWLELIGDLKERQKRGETSKEVLLA 650

  Fly   651 ENCAFAGKFKEAARLFLKCGQSSRALEMYTDLRMFDLAQEYIKDGTDQEKKELVRKRAEWAYSVK 715
            :..|||||:|||:||:.|.|.:|:||.||:||||||||||::|:|:..::|||:|:|||||.||.
Mosquito   651 DTYAFAGKYKEASRLYQKSGNNSKALAMYSDLRMFDLAQEFLKEGSAADRKELIRRRAEWACSVH 715

  Fly   716 EPRAAAELLLSAGENQKAIDIVAEQGWADVLYDIGRRLSLTERDSLESVAQNLKTLKALPLAAEI 780
            ||||||||||||||.::||:|||||||||||.||||||:.:||..||.:|.:|:.||||||||||
Mosquito   716 EPRAAAELLLSAGEPERAIEIVAEQGWADVLLDIGRRLAASERVPLELIASHLRRLKALPLAAEI 780

  Fly   781 FKKLGDEAQVVQLHIEVRDWPEAFRLAESLPELLPTVHYQHGQWLAETDQFIEAHQAYIKAGRTK 845
            ::|||:|.||||||:|.|||||||||||.||::||::|:||.|||||:||||.||:|||.||:..
Mosquito   781 YRKLGEEEQVVQLHVEARDWPEAFRLAEHLPKVLPSIHFQHAQWLAESDQFISAHEAYILAGKPH 845

  Fly   846 EANRLLKQLSNTAIVEERYLDASYFYWLLAKQHLDVYHAKEEQNPVDHH---LTEYKNHLRVAKV 907
            ||.:||:.|...|:.|||||||.|:.||.|||.|.:....|..  :|.:   ..||:..|:::.:
Mosquito   846 EATKLLRNLVECAVSEERYLDAGYYTWLRAKQALKLLEGDEAS--LDGNEAGAGEYRALLKLSSI 908

  Fly   908 YYAYSVIYSYMKEPFTTHSPVSLFNVSRFILNEVEHKGVPKGVSMFSVLFTLAKQAKFLQANKLC 972
            ||||:.|.:|:|||||:..|::|||.|||::|::.....|||:|:|:|.:||:||||.|.||||.
Mosquito   909 YYAYNTINAYLKEPFTSSPPLTLFNTSRFVVNQINGAMPPKGISLFAVYYTLSKQAKVLGANKLH 973

  Fly   973 LLINKRLQSLKPPAGVQEQIDLNFLNSKACKSGFNDPEELLPLCYKCSNYSQHLNSNCCPTCRQD 1037
            |.||.:|||||.|||:|||:|:::::|:||..||||||||||:||||||||.||:.|.||.|:|:
Mosquito   974 LQINNKLQSLKIPAGIQEQVDISYISSRACPGGFNDPEELLPMCYKCSNYSPHLHGNRCPNCQQE 1038

  Fly  1038 YIFSFVSFEILPLVQFYPEVDISDAEAERLLLAPAKHA--EDSDPF-NEDVASALPLSLDRNGLR 1099
            |:||:||||||||.:|.||..||:.:||||||||.|.|  :..|.| .||:....|.:|||..||
Mosquito  1039 YVFSYVSFEILPLAEFAPEAGISELDAERLLLAPPKSAAYDQQDQFIQEDIIDTYPSTLDREALR 1103

  Fly  1100 AIDPNHVLILKRRGKNVRNVYYRNILPDLQVTYCPQCLLLFYAEDFELQVLQKGHCPFCHTSSEK 1164
            ||||..|:|: |....:...||||:||:||:|.|.:|..:|::||||||.||||:||||.::.|.
Mosquito  1104 AIDPREVIIV-RGPAPLATRYYRNLLPELQITVCSECNQVFHSEDFELQFLQKGYCPFCRSTDET 1167

  Fly  1165 LM 1166
            ||
Mosquito  1168 LM 1169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oseg1	NP_648221.3	WD40	<22..296	CDD:441893	179/273 (66%)
		WD40 repeat	25..59	CDD:293791	21/33 (64%)
		WD40 repeat	65..99	CDD:293791	23/33 (70%)
		WD40 repeat	104..136	CDD:293791	22/31 (71%)
		WD40 repeat	144..214	CDD:293791	44/69 (64%)
		WD40 repeat	233..267	CDD:293791	22/33 (67%)
		WD40 repeat	275..301	CDD:293791	14/25 (56%)
		LapB	654..910	CDD:442196	160/258 (62%)
Oseg1	XP_316573.3	None