Protein Alignment CG13667 and NDOR1

DIOPT Version :10

• Sequence 1: NP_648220.1
• Gene: CG13667 / 38956
• FlyBaseID: FBgn0035890
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001137498.1
• Gene: NDOR1 / 27158
• HGNCID: 29838
• Length: 606
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 245/633 - (38%)
• Similarity: 349/633 - (55%)
• Gaps: 83/633 - (13%)

  Fly     2 RLLVLYGSQTGTAQDVAEQIWRESHQLGFQGPVLPFDEYDMTKLIEERLVVFVVATTGDGVEPDN 66
            :||||:||||||||||:|::.||:.:......|...|.|.:..||.|.||:||.||||.|..|||
Human     5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPPDN 69

  Fly    67 MKLAWRFLLKRSLPAQSLQGMQFACLGLGDSSYPKFNYAAKKLSKRLQNLGANSVCPVGLCDDQH 131
            ||..|||:.:::||:.:|..|.||.||||||||.|||:.||||.:||..||.:::.||.|.||||
Human    70 MKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQH 134

  Fly   132 DYGHLGVSLSWTKDLWTALKGI----SGLDE--------SKLS-----------NSHQTTVKWSV 173
            :.|.......|.:|||..:.|:    .||.|        ||.:           :..|.......
Human   135 ELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGS 199

  Fly   174 KELPKDSQ--IAPMDNLLWSQKQTAHSFKILDNQRTTAVDHFQDVRFLRLQCQTEDLSWEPGDVL 236
            :|.|.:|:  :|||                :.|||.|...||||||.:........:|:..|||:
Human   200 QEPPSESKPFLAPM----------------ISNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVV 248

  Fly   237 DVQPQNSDEAVQTFFDLIREHSLNFDESTIVEVSSAHQDMPLPIAYSNPLSLLQAAKFVWDLSAK 301
            .:||.||...||.|..:     |..|...:..:.....|:..|.....|.|:........|:::.
Human   249 LIQPSNSAAHVQRFCQV-----LGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASV 308

  Fly   302 PRQRFLEVLAQNCCDEMEKEKLLEFSSAEGIDDLVAYVNRPRRNLLEVLEDFRHATSSLTLQQLF 366
            ||:.|.|:||.....|:|:|||||||||:|.::|..|.|||||.:||||.||.|..:::....|.
Human   309 PRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLL 373

  Fly   367 EMMPLIQPRSFSIASDVSALS----LDLLVAVVEYKTIMHTPRLGLCSNWLKTLKSGTELSGV-- 425
            :::|:|:||:|||||  |.|:    |.:|||||:::|.:..||.||||:||.:|..|.....|
Human   374 DLIPVIRPRAFSIAS--SLLTHPSRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPL 436

  Fly   426 -VKRGTMVWPKDLSIPLIMVGPGTGIAPFRSIIQNRLYAQSKGATIGPLVVFFGCRNKAADFHFG 489
             |:.|::.:|:....|:||||||||:||||:.||.|: ||.:....    :|||||.:..||::.
Human   437 WVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERV-AQGQTGNF----LFFGCRWRDQDFYWE 496

  Fly   490 NDFSTWTDAKQVEAHT---AFSRD---------QDQKVYVQHLIAKNGAHLARLIKDLNAYIYVA 542
               :.|.:.::.:..|   ||||:         |:|||||||.:.:.|:.:..|:....||.|:|
Human   497 ---AEWQELEKRDCLTLIPAFSREQPPALFSALQEQKVYVQHRLRELGSLVWELLDRQGAYFYLA 558

  Fly   543 GNSNNMPKSVKEAFIEILDGD--------ADYVELMIKQRRYQEETWA 582
            ||:.:||..|.||.:.|...:        |.|:..:.:.||:|.||||
Human   559 GNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13667	NP_648220.1	Flavodoxin_1	5..136	CDD:425562	71/130 (55%)
		FNR_like	200..581	CDD:447143	152/407 (37%)
NDOR1	NP_001137498.1	CysJ	2..601	CDD:440138	240/626 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..207		3/18 (17%)