Protein Alignment CG13667 and NDOR1

DIOPT Version :9

• Sequence 1: NP_648220.1
• Gene: CG13667 / 38956
• FlyBaseID: FBgn0035890
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001137498.1
• Gene: NDOR1 / 27158
• HGNCID: 29838
• Length: 606
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 245/633 - (38%)
• Similarity: 349/633 - (55%)
• Gaps: 83/633 - (13%)

  Fly     2 RLLVLYGSQTGTAQDVAEQIWRESHQLGFQGPVLPFDEYDMTKLIEERLVVFVVATTGDGVEPDN 66
            :||||:||||||||||:|::.||:.:......|...|.|.:..||.|.||:||.||||.|..|||
Human     5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPPDN 69

  Fly    67 MKLAWRFLLKRSLPAQSLQGMQFACLGLGDSSYPKFNYAAKKLSKRLQNLGANSVCPVGLCDDQH 131
            ||..|||:.:::||:.:|..|.||.||||||||.|||:.||||.:||..||.:::.||.|.||||
Human    70 MKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQH 134

  Fly   132 DYGHLGVSLSWTKDLWTALKGI----SGLDE--------SKLS-----------NSHQTTVKWSV 173
            :.|.......|.:|||..:.|:    .||.|        ||.:           :..|.......
Human   135 ELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGS 199

  Fly   174 KELPKDSQ--IAPMDNLLWSQKQTAHSFKILDNQRTTAVDHFQDVRFLRLQCQTEDLSWEPGDVL 236
            :|.|.:|:  :|||                :.|||.|...||||||.:........:|:..|||:
Human   200 QEPPSESKPFLAPM----------------ISNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVV 248

  Fly   237 DVQPQNSDEAVQTFFDLIREHSLNFDESTIVEVSSAHQDMPLPIAYSNPLSLLQAAKFVWDLSAK 301
            .:||.||...||.|..:     |..|...:..:.....|:..|.....|.|:........|:::.
Human   249 LIQPSNSAAHVQRFCQV-----LGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASV 308

  Fly   302 PRQRFLEVLAQNCCDEMEKEKLLEFSSAEGIDDLVAYVNRPRRNLLEVLEDFRHATSSLTLQQLF 366
            ||:.|.|:||.....|:|:|||||||||:|.::|..|.|||||.:||||.||.|..:::....|.
Human   309 PRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLL 373

  Fly   367 EMMPLIQPRSFSIASDVSALS----LDLLVAVVEYKTIMHTPRLGLCSNWLKTLKSGTELSGV-- 425
            :::|:|:||:|||||  |.|:    |.:|||||:::|.:..||.||||:||.:|..|.....|
Human   374 DLIPVIRPRAFSIAS--SLLTHPSRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPL 436

  Fly   426 -VKRGTMVWPKDLSIPLIMVGPGTGIAPFRSIIQNRLYAQSKGATIGPLVVFFGCRNKAADFHFG 489
             |:.|::.:|:....|:||||||||:||||:.||.|: ||.:....    :|||||.:..||::.
Human   437 WVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERV-AQGQTGNF----LFFGCRWRDQDFYWE 496

  Fly   490 NDFSTWTDAKQVEAHT---AFSRD---------QDQKVYVQHLIAKNGAHLARLIKDLNAYIYVA 542
               :.|.:.::.:..|   ||||:         |:|||||||.:.:.|:.:..|:....||.|:|
Human   497 ---AEWQELEKRDCLTLIPAFSREQPPALFSALQEQKVYVQHRLRELGSLVWELLDRQGAYFYLA 558

  Fly   543 GNSNNMPKSVKEAFIEILDGD--------ADYVELMIKQRRYQEETWA 582
            ||:.:||..|.||.:.|...:        |.|:..:.:.||:|.||||
Human   559 GNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13667	NP_648220.1	CysJ	2..581	CDD:223446	242/630 (38%)
		Flavodoxin_1	5..136	CDD:278677	71/130 (55%)
		FNR_like	200..581	CDD:297884	152/407 (37%)
NDOR1	NP_001137498.1	CysJ	3..605	CDD:223446	242/630 (38%)
		Flavodoxin_1	8..145	CDD:278677	71/136 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..207		3/18 (17%)
		FNR_like	212..605	CDD:297884	154/423 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160336
Domainoid	1	1.000	153	1.000	Domainoid score	I4314
eggNOG	1	0.900	-	-		E1_COG0369
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7144
Inparanoid	1	1.050	390	1.000	Inparanoid score	I2014
Isobase	1	0.950	-	0	Normalized mean entropy	S2543
OMA	1	1.010	-	-		QHG53742
OrthoDB	1	1.010	-	-		D318396at2759
OrthoFinder	1	1.000	-	-		FOG0004190
OrthoInspector	1	1.000	-	-		oto90553
orthoMCL	1	0.900	-	-		OOG6_100390
Panther	1	1.100	-	-	LDO	PTHR19384
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3452
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720