DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13667 and ndor1

DIOPT Version :9

Sequence 1:	NP_648220.1	Gene:	CG13667 / 38956	FlyBaseID:	FBgn0035890	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001120408.1	Gene:	ndor1 / 100145485	XenbaseID:	XB-GENE-956252	Length:	598	Species:	Xenopus tropicalis

Alignment Length:	612	Identity:	263/612 - (42%)
Similarity:	351/612 - (57%)	Gaps:	51/612 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLVLYGSQTGTAQDVAEQIWRESHQLGFQGPVLPFDEYDMTKLIEERLVVFVVATTGDGVEPDNM 67
            ||:|||||||||:|:|.::.||:.:..||..:...|||.:..||.|.|||||.||||.|..||||
Frog     6 LLILYGSQTGTAEDLAGRLGREAKRHHFQCRMESLDEYRVADLIHEPLVVFVCATTGQGDPPDNM 70

  Fly    68 KLAWRFLLKRSLPAQSLQGMQFACLGLGDSSYPKFNYAAKKLSKRLQNLGANSVCPVGLCDDQHD 132
            |..|||:.:|:||..:|..|.:|.||||||||||||:.||||.||||.|||..:.|..|.|||||
Frog    71 KNFWRFIFRRNLPHNALCRMDYAVLGLGDSSYPKFNFIAKKLHKRLQQLGACPLLPPALGDDQHD 135

  Fly   133 YGHLGVSLSWTKDLWTALKGI----SGLD---------ESKLSNSHQTTV---KWSVKELPKDSQ 181
            .|.......|.||||:.:..|    .||:         ...|....:.|:   ..|.:||.:||.
Frog   136 LGPDAAVDPWLKDLWSKILSIYPLPPGLNIISEDILLPPKYLLRLLEETIGQDDLSGEELERDSN 200

  Fly   182 IAPMDNLLWSQKQTAHSF--KILDNQRTTAVDHFQDVRFLRLQCQTEDLSWEPGDVLDVQPQNSD 244
            ..       :....:|.|  .::.|||.||:|||||||.:........|.:.||||..|||:||.
Frog   201 NT-------TPASESHPFPAPVVSNQRVTALDHFQDVRLIEFDISGSALQFSPGDVAMVQPRNSP 258

  Fly   245 EAVQTFFDLIREHSLNFDEST--IVEVSSAHQDMPLPIAYSNPLSLLQAAKFVWDLSAKPRQRFL 307
            ..||....|:|     .|..|  :||.|.....:|..:|....:.  |.|:...||.|.||:.|.
Frog   259 PHVQQLCSLLR-----LDPRTRFVVEASDPEAAVPAQLAELQCIG--QLAERYLDLCAVPRRSFF 316

  Fly   308 EVLAQNCCDEMEKEKLLEFSSAEGIDDLVAYVNRPRRNLLEVLEDFRHATSSLTLQQLFEMMPLI 372
            ::|:....||:|:|||.||.||.|.::|.:|.|||||.|||||.||.|.|..:....|.|::|.:
Frog   317 QLLSHFAPDELEREKLREFGSAGGQEELFSYCNRPRRTLLEVLVDFPHTTRCIPATYLLELIPRM 381

  Fly   373 QPRSFSIASDVSAL--SLDLLVAVVEYKTIMHTPRLGLCSNWLKTL-KSGTELSGV-VKRGTMVW 433
            :||:|||||.:.||  :|.:|||||:|::.:..||.||||.||.:| ..|.|...: ||||:|.:
Frog   382 RPRAFSIASSMQALPNALQILVAVVQYRSKLIEPRRGLCSTWLASLPPRGRERVPIWVKRGSMTF 446

  Fly   434 PKDLSIPLIMVGPGTGIAPFRSIIQNRLYAQSKGATIGPLVVFFGCRNKAADFHFGNDFSTWTDA 498
            |.:...||:|||||||:||||:.:|.|.....:.:.:     |||||.|:.||:|..::......
Frog   447 PLEPGTPLVMVGPGTGVAPFRAAVQERAANGKRWSCL-----FFGCRGKSKDFYFEKEWEDLVTG 506

  Fly   499 KQVEAHTAFSRDQDQKVYVQHLIAKNGAHLARLIKDLNAYIYVAGNSNNMPKSVKEAFIEILDG- 562
            ..:...|||||||:.|||||..|.:|.|.|..|:.:...|.|:|||:.:||..|.:|...:|..
Frog   507 GFLTLFTAFSRDQEDKVYVQRRIRENSALLWDLLANRQGYFYIAGNAKSMPNEVTDALKWVLQSE 571

  Fly   563 ------DAD-YVELMIKQRRYQEETWA 582
                  ||: ||..|.|.||:|.|||:
Frog   572 GGLSAPDAEQYVVAMEKSRRFQSETWS 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13667	NP_648220.1	CysJ	2..581	CDD:223446	261/609 (43%)
		Flavodoxin_1	5..136	CDD:278677	76/130 (58%)
		FNR_like	200..581	CDD:297884	166/394 (42%)
ndor1	NP_001120408.1	CysJ	4..597	CDD:223446	261/609 (43%)
		Flavodoxin_1	8..145	CDD:278677	76/136 (56%)
		FNR_like	214..597	CDD:297884	166/394 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	164	1.000	Domainoid score	I3909
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7144
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318396at2759
OrthoFinder	1	1.000	-	-		FOG0004190
OrthoInspector	1	1.000	-	-		oto104352
Panther	1	1.100	-	-	LDO	PTHR19384
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3452
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.110