DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mkg-p and HESO1

DIOPT Version :9

Sequence 1:	NP_001286981.1	Gene:	mkg-p / 38955	FlyBaseID:	FBgn0035889	Length:	659	Species:	Drosophila melanogaster
Sequence 2:	NP_001318386.1	Gene:	HESO1 / 818559	AraportID:	AT2G39740	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	469	Identity:	108/469 - (23%)
Similarity:	175/469 - (37%)	Gaps:	123/469 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 DLENMKTCFGHVRNCIEKE--MRGRVRVFPFGSLVTGLALKESDIDLFLEPNGNQPPLFHNQLYN 159
            |.:...|....:|:.::..  :|| ..|.||||.|:.|..:..|:|:.::.......||..:...
plant    24 DRDTRITVIDQLRDVLQSVECLRG-ATVQPFGSFVSNLFTRWGDLDISVDLFSGSSILFTGKKQK 87

  Fly   160 KT--SHFLRRSKCFADVFTIR---HASVPIIRCKHQLTGLNIDINMSNPNSIYNSRFVGELMFRN 219
            :|  .|.||..:.....:.::   ||.|||::.......::.||::.|.:.:..|||:..:...:
plant    88 QTLLGHLLRALRASGLWYKLQFVIHARVPILKVVSGHQRISCDISIDNLDGLLKSRFLFWISEID 152

  Fly   220 ERIRELCLFLKIWAKKLKLISH-------GGMTSYCLISLIIVNLQVNRLVPSVKELQSLCPPVI 277
            .|.|:|.|.:|.|||     :|       |...||.|..|:|.:.|.             |.|.|
plant   153 GRFRDLVLLVKEWAK-----AHNINDSKTGTFNSYSLSLLVIFHFQT-------------CVPAI 199

  Fly   278 LSGVNYAYSL----DLT----------PPIPA---------------RLTTLDLLKNFFIYYCTV 313
            |..:...|..    |||          ..:.|               |.:..:||.:||..:..:
plant   200 LPPLRVIYPKSAVDDLTGVRKTAEESIAQVTAANIARFKSERAKSVNRSSLSELLVSFFAKFSDI 264

  Fly   314 NF--DKSVLSPFLG--GCVDKETTLGMPGGFPEYDEQQKLVHDAIGAPPDAFQLDRAMCVQDPFE 374
            |.  .:..:.||.|  ..:...|| .:|..:                         ::.|:||||
plant   265 NVKAQEFGVCPFTGRWETISSNTT-WLPKTY-------------------------SLFVEDPFE 303

  Fly   375 LSRNVAKSVSISNLCYFRQCLVLAAQ----ACSDQE----LTSQ--PEKLYDYLLFGLADKLVAD 429
            ...|.|:|||..||....|...:.::    .|:...    ||.|  .|.||..:  .|..:..|:
plant   304 QPVNAARSVSRRNLDRIAQVFQITSRRLVSECNRNSIIGILTGQHIQESLYRTI--SLPSQHHAN 366

  Fly   430 KI--VADKRSERATPRKQQKIEN----------AHVQPPIVDETQE---TKVAEVGVCGTPPLVR 479
            .:  |.:...: |.|:.||..:|          .| .||:.....:   |:.....:.|.||:..
plant   367 GMHNVRNLHGQ-ARPQNQQMQQNWSQSYNTPNPPH-WPPLTQSRPQQNWTQNNPRNLQGQPPVQG 429

  Fly   480 S--HVITPTTNDVK 491
            .  .|||.|....|
plant   430 QTWPVITQTQTQQK 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mkg-p	NP_001286981.1	NT_PAP_TUTase	104..216	CDD:143392	29/118 (25%)
HESO1	NP_001318386.1	TRF4	11..436	CDD:227585	104/460 (23%)
HESO1	NP_001318386.1	Pro-rich	<372..507	CDD:373673	17/74 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12271
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870