DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mkg-p and tut7

DIOPT Version :9

Sequence 1:	NP_001286981.1	Gene:	mkg-p / 38955	FlyBaseID:	FBgn0035889	Length:	659	Species:	Drosophila melanogaster
Sequence 2:	XP_021332039.1	Gene:	tut7 / 562358	ZFINID:	ZDB-GENE-101209-1	Length:	1155	Species:	Danio rerio

Alignment Length:	538	Identity:	109/538 - (20%)
Similarity:	196/538 - (36%)	Gaps:	151/538 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CMVCAAPFRSMQDCLAHELIKHASKPQKQLRQRLNAITKLFNSAQSQSERQELREALEWSESGGH 86
            |..|......:...|:|...:...|..|:| |:|..:..:...|:...  ..:..|||
Zfish   142 CDKCKVFCEDISPALSHIRERSHRKKAKEL-QKLALLLSIPPPAKPHC--LSVSSALE------- 196

  Fly    87 LCTVLNFFACDLENMKTCFGHVRNCIEKEMRGRVRVFP------FGSLVTGLALKESDIDLFLE- 144
              :::..|..:.|::|. ..::...|||.:.   .|.|      :||..|....|:||:::.::
Zfish   197 --SIVTEFGLNDEDLKQ-RQNILALIEKVLH---PVLPECQFRLYGSSSTKFGFKDSDVNIDVKF 255

  Fly   145 PNGNQPPLFHNQLYNKTSHFLRRSKCFADVFTIRHASVPIIRCKHQLTGLNIDINMSNPNSIYNS 209
            |:..|    |..:.......|.:|..|..|....|..:|::.||.:.:||...::..|.::...:
Zfish   256 PSHFQ----HPDILLAAQEHLSKSSLFDSVEGDFHRRMPVVVCKEKASGLICKVSAGNESACLTT 316

  Fly   210 RFVGELMFRNERIRELCLFLKIWAK--KLKLISHGGMTSYCLISLIIVNLQVNR--LVPSVKELQ 270
            .::.|:.....::..|.:..:.|||  .:..:..||:.|||...::|..||..:  ::|:.  |:
Zfish   317 AYLSEMADLEPQLVPLVICFRYWAKICCVDQMEEGGLPSYCFALMVISFLQRRKEPILPTY--LE 379

  Fly   271 SLCPPV------ILSGVNYAY-----------SLDL-------TPPIPARLTTLDLLKNFFI--- 308
            |:..|:      .|:||...:           |||.       ..|:..:..:..||...:|
Zfish   380 SMGFPLSKLKSFSLTGVEKGHVLWVYDQTNDSSLDKDKAVKKGKAPLAFKSRSPVLLGKLWIELL 444

  Fly   309 -YYC-TVNFDKSVLSPFLGGCVDKETTLGMPGGFPEYDEQQKLVHDAIGAPPDAFQLDRAMCVQD 371
             ||. .....:.::|....|                     :|..|....|      .:.:.::|
Zfish   445 RYYALEFQIPEKIISVRTNG---------------------ELWRDLKDWP------KKRIAIED 482

  Fly   372 PFELSRNVAKSVSISNLCYFRQCLVLAAQACSDQELTSQPEKLYDYLL---------FGLADKLV 427
            ||.:.||||::                        |.||  .::||||         |....|..
Zfish   483 PFTVQRNVART------------------------LNSQ--TMFDYLLHCLKTTYKYFASPSKST 521

  Fly   428 ADKIVADKRSERATPRKQQKIENAHVQPPIVDETQETKVAEVGVCGTPPLVRSHVITPTT----N 488
            |.|:....||.........|              :..||:..|:.|  |.|:|   :|.:    .
Zfish   522 AGKMSTSSRSVSVNHADSVK--------------KSAKVSSEGLNG--PRVKS---SPHSAEDLE 567

  Fly   489 DVKCLRSIVLVKNTENDQ 506
            |..||    :.::.|.|:
Zfish   568 DSDCL----IEQDDEEDE 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mkg-p	NP_001286981.1	NT_PAP_TUTase	104..216	CDD:143392	26/118 (22%)
tut7	XP_021332039.1	PAP_assoc	150..>499	CDD:332051	83/423 (20%)
		NT_PAP_TUTase	211..323	CDD:143392	26/119 (22%)
		NT_PAP_TUTase	733..838	CDD:143392
		PAP_assoc	902..955	CDD:309089
		AIR1	<1009..1088	CDD:331526
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010