DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mkg-p and Mtpap

DIOPT Version :9

Sequence 1:	NP_001286981.1	Gene:	mkg-p / 38955	FlyBaseID:	FBgn0035889	Length:	659	Species:	Drosophila melanogaster
Sequence 2:	XP_038951672.1	Gene:	Mtpap / 307050	RGDID:	1310900	Length:	584	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	106/416 - (25%)
Similarity:	174/416 - (41%)	Gaps:	101/416 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 QLRQRLNAIT-KLFNSAQSQS--ERQELREALEWSES-GGHLCTVLNFFACDLENMK----TC-- 104
            :|:...|.:: :.|..|.|||  ..::|.|.|.::|| ...|..:|..|....||::    ||
  Rat   152 KLKNPSNQVSGQSFVQADSQSPPSSKKLFELLSYAESIDAQLTALLKAFQLTEENVRLRHLTCSL 216

  Fly   105 -----FGHVRNCIEKEMRGRVRVFPFGSLVTGLALKESDIDLF--LEPNGNQPP-------LFHN 155
                 ..:..:|:         |:||||.|........|:|:|  |:..||...       |...
  Rat   217 IEDIAAAYFPSCV---------VWPFGSSVNTFGKLGCDLDMFLDLDETGNLSDHKNTGNFLMEF 272

  Fly   156 QLYNKTSHFLRRSKCFA--------------DVFTIRHASVPIIRCKHQLTGLNIDINMSNPNSI 206
            |:.|..|..:...|..:              .|..|.:|..|::|..||.:|...|:..:|..::
  Rat   273 QVKNVPSERVATQKILSVIGECLDNFGPGCVGVQKILNARCPLVRFSHQGSGFQCDLTANNSIAL 337

  Fly   207 YNSRFVGELMF----RNERIRELCLFLKIWAKKLKLISH---GGMTSYCLISLIIVNLQVNR--L 262
            .:|    ||::    .:.|:|.|...::.||:...|.|.   ..:|::.|..::|..||...  :
  Rat   338 KSS----ELLYIYGSLDSRVRALVFGVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPI 398

  Fly   263 VPSVKELQSLCPP---VILSGVNYAYSLDLTPPIPARLT-TLD-LLKNFFIYYCTVNFDKSVLSP 322
            :|::..|:|:...   .||.|.|..:..|:....|:..| ||: |||.||.|:....|:|:.::.
  Rat   399 LPTLDSLKSMADAEDRCILEGNNCTFIQDINKIKPSGNTETLELLLKEFFEYFGNFAFNKNSINI 463

  Fly   323 FLGGCVDKETTLGMPGGFPEYDEQQKLVHDAIGAPPDAFQLDRAMCVQDPFELSRNVAKSVSISN 387
            ..|                  .||.|         ||:..|    .:|:|||.|.|::|:||.:.
  Rat   464 RQG------------------REQNK---------PDSSPL----YIQNPFETSLNISKNVSQNQ 497

  Fly   388 LCYFRQCLVLAAQAC--SDQELTSQP 411
            |..|   :.||..:.  .:||...||
  Rat   498 LQKF---VELARDSAWILEQEKKDQP 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mkg-p	NP_001286981.1	NT_PAP_TUTase	104..216	CDD:143392	31/141 (22%)
Mtpap	XP_038951672.1	RL	63..132	CDD:407669
		TRF4	184..>496	CDD:227585	88/355 (25%)
		NT_PAP_TUTase	209..347	CDD:143392	33/150 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770