DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mkg-p and cid1

DIOPT Version :9

Sequence 1:	NP_001286981.1	Gene:	mkg-p / 38955	FlyBaseID:	FBgn0035889	Length:	659	Species:	Drosophila melanogaster
Sequence 2:	NP_594901.1	Gene:	cid1 / 2542420	PomBaseID:	SPAC19D5.03	Length:	405	Species:	Schizosaccharomyces pombe

Alignment Length:	389	Identity:	86/389 - (22%)
Similarity:	160/389 - (41%)	Gaps:	74/389 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 DLENMKTCFGHVRNCIEKEMRGRVRVFPFGSLVTGLALKESDIDLFLEPNGNQPPLFHNQLYNKT 161
            :.:..:.....:|.|: |.:.....:..||||.:|||||.||:||.:        |..:::.:.|
pombe    61 EFKEKRAALDTLRLCL-KRISPDAELVAFGSLESGLALKNSDMDLCV--------LMDSRVQSDT 116

  Fly   162 SHFLRRSKCFADVFT---IRHASVPIIRCKHQL-----TGLNIDINMSNPNSIYNSRFVGELMFR 218
            .......:..|:.|.   ::.|.:|||:.....     .....||..:|..:|:|:..:......
pombe   117 IALQFYEELIAEGFEGKFLQRARIPIIKLTSDTKNGFGASFQCDIGFNNRLAIHNTLLLSSYTKL 181

  Fly   219 NERIRELCLFLKIWAKKLKLIS--HGGMTSYCLISLIIVNLQVNRLVPSVKELQSLCPPVILS-- 279
            :.|::.:.|.:|.|||:.::.|  .|.::||..:.:::..| ::.:.|.|      .|.::||
pombe   182 DARLKPMVLLVKHWAKRKQINSPYFGTLSSYGYVLMVLYYL-IHVIKPPV------FPNLLLSPL 239

  Fly   280 ---------GVNYAYSLDLTPPIPARLTTLDLLKNFFIYYCTVNFDKSVLSPFLGGCVDKETTLG 335
                     .|.:...|:..||.....:...||..||.:| ...|:..          :|..|..
pombe   240 KQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFY-AYKFEPR----------EKVVTFR 293

  Fly   336 MPGGFPEYDEQQKLVHDAIGAPPDAFQL--DR-AMCVQDPFELSRNVAKSVSISNLCYFRQCLVL 397
            .|.|:  ..:|:|....|......|.|:  || .:.::||||:|.||.::||.|.|...|...:.
pombe   294 RPDGY--LTKQEKGWTSATEHTGSADQIIKDRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMA 356

  Fly   398 AAQACSDQELTSQPEKLYDYLLFGLADKLVADKIVADKRSERATPRKQQKIENAHVQPPIVDET 461
            |::..:.:......:.|::                     |...|.::||..:......:::||
pombe   357 ASRLLNSRSYPIPYDSLFE---------------------EAPIPPRRQKKTDEQSNKKLLNET 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mkg-p	NP_001286981.1	NT_PAP_TUTase	104..216	CDD:143392	29/119 (24%)
cid1	NP_594901.1	TRF4	1..405	CDD:227585	86/389 (22%)
		NT_PAP_TUTase	65..178	CDD:143392	29/121 (24%)
		PAP_assoc	267..336	CDD:281779	21/81 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870