Protein Alignment mkg-p and TUT4

DIOPT Version :9

• Sequence 1: NP_001286981.1
• Gene: mkg-p / 38955
• FlyBaseID: FBgn0035889
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_005270733.1
• Gene: TUT4 / 23318
• HGNCID: 28981
• Length: 1652
• Species: Homo sapiens
• Alignment Length: 581
• Identity: 126/581 - (21%)
• Similarity: 209/581 - (35%)
• Gaps: 166/581 - (28%)

  Fly     8 STSPPGDGDGNLVLCMVCAAPFRSMQDCLAHELIKHASKPQKQLRQRLNAITKL-----FNSAQS 67
            |..||      .::|.:|.....|..|| ..:..|...||...:..|...|..|     |:....
Human   907 SGKPP------TIVCSICKKDGHSKNDC-PEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSP 964

  Fly    68 QSERQELREALEWSESGGHLCTVLNFFACDLENMKTCFGHVRNCIEKEMRGRVRVFPFGSLVTGL 132
            ....|..||.:                ...||..          |:||...:.|:..|||...|.
Human   965 PCSEQHNREQI----------------LIGLEKF----------IQKEYDEKARLCLFGSSKNGF 1003

  Fly   133 ALKESDID--LFLEPNGNQPPLFHNQLYNKTSHFLRRSKCFADVFTIRHASVPIIRCKHQLTGLN 195
            ..::||:|  :.||.:.|...|...::....:..|:|.....::..|..|.|||::.:|:.:||.
Human  1004 GFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLE 1068

  Fly   196 IDINMSNPNSIYNSRFVGELMFRNERIRELCLFLKIWAKKLKL--ISHGGMTSYCLISLIIVNLQ 258
            .||::.|..:.:|:|.:......:.|::.|...:|::||:..:  .|.|.::||..|.:::..||
Human  1069 GDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQ 1133

  Fly   259 VNRLVPSVKELQSL-----CPPVILSGVNYAYSLDLTPPIPARLTTL--------DLLKNFFIYY 310
             .|..|.:..||.:     .|..::.|.| |:..|.|..:..||.:|        :|......:|
Human  1134 -QRKPPVIPVLQEIFDGKQIPQRMVDGWN-AFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFY 1196

  Fly   311 CTVNFDKSVLSPFLGGCVDKETTLGMPGGFPEY---DEQQKLVHDAIGAPPDAFQ---LDRAMCV 369
             |..||                       |.||   ..|:||:        ..|:   ..:.:.:
Human  1197 -TEEFD-----------------------FKEYVISIRQKKLL--------TTFEKQWTSKCIAI 1229

  Fly   370 QDPFELSRNVAKSVS--ISNLC------------------------YFRQCLVLAAQACSDQELT 408
            :|||:|:.|:...||  ::|..                        ||....||     :|.||.
Human  1230 EDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVL-----TDGELA 1289

  Fly   409 SQPE------KLYDY----------LLFGLADKLVADKIVADKRSERATPRKQQKIENAHVQPPI 457
            ....      |:..|          |||.|..|        |...|: ...:::|.....:.|..
Human  1290 PNDRCCRVCGKIGHYMKDCPKRKSSLLFRLKKK--------DSEEEK-EGNEEEKDSRDVLDPRD 1345

  Fly   458 VDET---QETKVAEVGVCGTPPLVRSHVITPTTNDVKCLR-------SIVLVKNTENDQSI 508
            :.:|   ::.:.....:||....||..     ..:||..|       :..||:|..|.|.:
Human  1346 LHDTRDFRDPRDLRCFICGDAGHVRRE-----CPEVKLARQRNSSVAAAQLVRNLVNAQQV 1401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mkg-p	NP_001286981.1	NT_PAP_TUTase	104..216	CDD:143392	30/113 (27%)
TUT4	XP_005270733.1	NT_PAP_TUTase	375..487	CDD:143392
		PAP_assoc	628..677	CDD:281779
		NT_PAP_TUTase	971..1089	CDD:143392	34/143 (24%)
		PAP_assoc	1184..1237	CDD:281779	16/84 (19%)
		PTZ00368	<1280..1375	CDD:173561	21/113 (19%)
		CytochromB561_N	1375..>1516	CDD:286826	8/27 (30%)
		DUF1421	<1383..1650	CDD:284607	5/19 (26%)
		FAM75	1423..>1484	CDD:291323

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8153
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860