DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mkg-p and cid-1

DIOPT Version :9

Sequence 1:	NP_001286981.1	Gene:	mkg-p / 38955	FlyBaseID:	FBgn0035889	Length:	659	Species:	Drosophila melanogaster
Sequence 2:	NP_498099.1	Gene:	cid-1 / 175707	WormBaseID:	WBGene00019629	Length:	1425	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	79/308 - (25%)
Similarity:	133/308 - (43%)	Gaps:	72/308 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VRNCIEKEMRGRVRVFPFGSLVTGLALKESDIDLFLE-PNGNQPP--LFHNQLYNKTSHFLRRSK 169
            :::.:.|..|..|.:..|||::|||::..||||:.|. .:|:.||  |...::..||...||:..
Worm  1037 LQSFLRKNYREDVTLTTFGSVMTGLSVNCSDIDICLRFGDGDVPPKDLTAKEVIQKTESVLRKCH 1101

  Fly   170 CFADVFTIRHASVPIIRCKHQLTG---LNIDINMSNPNSIYNSRFVGE--LMFRNERIRELCLFL 229
            ....|..|..|.|||::.:.:|:.   :::||:..|..:|||:..:.|  |...::|..:|.||:
Worm  1102 LVKRVQAIVTAKVPIVKFQVKLSNGAIIDVDISYYNILAIYNTALLKEYSLWTPDKRFAKLALFV 1166

  Fly   230 KIWAKKLKL--ISHGGMTSYCLISLIIVNLQVNRLVPSVKELQSLCPPVILSGVNYAYSLD---- 288
            |.|||..::  .|.|.::|||.:.::|..||             .|.|.:|..:...:..|
Worm  1167 KTWAKNCEIGDASRGSLSSYCHVIMLISYLQ-------------NCDPPVLPRLQEDFRSDNRER 1218

  Fly   289 ----------------LTPPIPA-RLTTLDLLKNFFIYYCTVNFDKSVLSPFLGGCVDKETTLGM 336
                            |....|. :.:...||..:|.||...:|...|:.     |..:.....|
Worm  1219 RLVDNWDTSFAQVETSLLQRWPKNKESCAQLLIGYFDYYSRFDFRNFVVQ-----CRREMILSKM 1278

  Fly   337 PGGFPEYDEQQKLVHDAIGAPPDAFQLDRAMCVQDPFELSRNVAKSVS 384
            ...:|                       |.:||:|||:||.|::..|:
Worm  1279 EKEWP-----------------------RPLCVEDPFDLSHNLSSGVN 1303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mkg-p	NP_001286981.1	NT_PAP_TUTase	104..216	CDD:143392	36/115 (31%)
cid-1	NP_498099.1	PAP_assoc	574..625	CDD:367682
		NT_PAP_TUTase	1029..1151	CDD:143392	36/113 (32%)
		TRF4	1034..>1317	CDD:227585	79/308 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910