Protein Alignment mkg-p and TENT2

DIOPT Version :10

• Sequence 1: NP_648219.1
• Gene: mkg-p / 38955
• FlyBaseID: FBgn0035889
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_001336478.1
• Gene: TENT2 / 167153
• HGNCID: 26776
• Length: 509
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 93/406 - (22%)
• Similarity: 164/406 - (40%)
• Gaps: 114/406 - (28%)

  Fly    25 CAAPFRSMQDCLAHELIKHASKPQKQLRQRLNAITKLFNSAQSQSERQELREALEWSESGGHLCT 89
            |..|||.:......|:....:|  .:|.|:   |.:||.:.|.|
Human   132 CVPPFREIAFLEPREITLPEAK--DKLSQQ---ILELFETCQQQ--------------------- 170

  Fly    90 VLNFFACDLENMKTCFGHVRNCIEKEMR---GRVRVFPFGSLVTGLALKESDIDLFLEPNGNQPP 151
                 ..||:..:.|    |..:::|::   .:.|:|..||.:.|...:.||.||.|..  .:.|
Human   171 -----ISDLKKKELC----RTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSDGDLCLVV--KEEP 224

  Fly   152 LFHNQLYNKT----------SHFLRR-------SKCFA-DVFTIR-----------------HAS 181
            .|. |:..||          .||..|       ..|.: ||..::                 .|.
Human   225 CFF-QVNQKTEARHILTLVHKHFCTRLCKSDMPQVCMSPDVTLLKMPLTLSSAGYIERPQLIRAK 288

  Fly   182 VPIIRCKHQLTGLNIDINMSNPNSIYNSRFVGELMFRNERIRELCLFLKIWAK--KLKLISHGGM 244
            |||::.:.:::.:..|:|::|...|.|:..:....:...|:|.|.|.:|.||.  ::...|.|.:
Human   289 VPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHQINDASRGTL 353

  Fly   245 TSYCLISLIIVNLQV--NRLVPSVKEL--QSLCPPVILSGVNYAYSLDLTPPIPARLTTL-DLLK 304
            :||.|:.:::..||.  ..::||::::  :|..|.:.|..|:.| ..::.|.:....:.| |||.
Human   354 SSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSPAIQLHLVHQA-PCNVPPYLSKNESNLGDLLL 417

  Fly   305 NFFIYYCTVNFDKSVLSPFLGGCVDKETTLGMPGGFPEYDEQQKLVHDAIGAP-PDAFQ-LDRAM 367
            .|..||.| .||                          ::.|...|.:|...| ||..: .::.:
Human   418 GFLKYYAT-EFD--------------------------WNSQMISVREAKAIPRPDGIEWRNKYI 455

  Fly   368 CVQDPFELSRNVAKSV 383
            ||::||: ..|.|::|
Human   456 CVEEPFD-GTNTARAV 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mkg-p	NP_648219.1	NT_PAP_TUTase	104..216	CDD:143392	33/149 (22%)
TENT2	NP_001336478.1	TRF4	154..>493	CDD:227585	87/382 (23%)