DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon66Cii and prss60.1

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	241	Identity:	76/241 - (31%)
Similarity:	112/241 - (46%)	Gaps:	29/241 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MQGRITNGYPAEEGKAPYTVGL--GFSGGWWCGGSIIAHDWVLTAEHCIG--DADSVTVYFGATW 96
            :..||..|..|.:|..|:.|.|  ...||.:||||:|..:|||||.||:.  ...|:.|:.|.|.
Zfish    30 LNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEWVLTAAHCLPRITTSSLLVFLGKTT 94

  Fly    97 ----------RTNAQFTHWVGNGNFIKHSSADIALIRIPH-VDFWHMVNKVELPSYNDRYNDYNE 150
                      ||.:..|......|....:  ||||:.:.. |.|.:.:..|.|.:.|..:.:...
Zfish    95 QQGVNTYEINRTVSVITVHPSYNNLTNEN--DIALLHLSSAVTFSNYIRPVCLAAQNSVFPNGTS 157

  Fly   151 WWAVACGWGGTYDG--SPLPDYLQCVDLQIIHNSECSGYY--GSVGDNILCV-RTPDGKSTCGGD 210
            .|..  |||....|  .|.|..||...:.::.|.:|:...  |||.:|::|. ....|:.||.||
Zfish   158 SWIT--GWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGSGSVTNNMICAGLLQGGRDTCQGD 220

  Fly   211 SGGPLVTHDGTKLV--GVTNFGSVAGCQSG-APAGFQRVTYHLDWI 253
            ||||:|:......|  |:|::|  .||... :|..:.||:.:..||
Zfish   221 SGGPMVSKQCLVWVQSGITSWG--YGCADPYSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	74/236 (31%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	75/237 (32%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	74/236 (31%)
		Tryp_SPc	34..267	CDD:238113	75/237 (32%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910