DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and tmprss4

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_012822151.1	Gene:	tmprss4 / 733869	XenbaseID:	XB-GENE-940762	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	75/251 - (29%)
Similarity:	108/251 - (43%)	Gaps:	48/251 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TKDMQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIG----DADSVTVYFG 93
            |...|.||..|..::..|.|:.|.|.:.|...|||||:...|:|.|.||..    ..|...|.:|
Frog   545 TGHKQERIIGGSNSDILKYPWQVSLQYMGQHICGGSILNSRWILCAAHCFDRGQRQVDRWRVQYG 609

  Fly    94 ATWRTNAQFTHWVG--------NGNFIKHSSA-DIALIRI-PHVDFWHMVNKVELPSYNDR---- 144
            .|     ..|:..|        |..::..... ||||::: ..:.....|..|.||.|::.
Frog   610 IT-----TLTYLFGTFVDKIFLNSKYVTDQKPNDIALLQLKSDIVASASVQPVCLPGYDNNLVVG 669

  Fly   145 ---YNDYNEWWAVACGWGGTYD-GSPLPDYLQCVDLQIIHNSECSGYY-GSVGDNILCV-RTPDG 203
               |         ..|||.|.: |:.|...||.|.:.:|.::.|:..| |.:.|.:||. :...|
Frog   670 AVLY---------VTGWGHTVEGGAALASQLQEVAISLISSTTCNQEYGGQILDTMLCAGKIAGG 725

  Fly   204 KSTCGGDSGGPLVT---HDGTKLVGVTNFGSVAGCQSGAP---AGFQRVTYHLDWI 253
            ..||.||||||||:   ....:.||:.::|.  ||  |.|   ..:..|...|:||
Frog   726 ADTCQGDSGGPLVSLGQSSHWEQVGIVSWGD--GC--GRPNRVGVYTDVQSFLNWI 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	71/243 (29%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	72/244 (30%)
tmprss4	XP_012822151.1	ATF7IP_BD	<110..233	CDD:293393
		PHA03193	<206..340	CDD:177555
		LDLa	402..434	CDD:238060
		SRCR_2	453..545	CDD:292133	75/251 (30%)
		SRCR	464..541	CDD:278931
		Tryp_SPc	551..777	CDD:214473	71/243 (29%)
		Tryp_SPc	552..777	CDD:238113	70/242 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000