DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and tmprss5

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	241	Identity:	76/241 - (31%)
Similarity:	113/241 - (46%)	Gaps:	29/241 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGD-----ADSVTVYFGATWRT 98
            ||..|..|..|:.|:.|.|.::....||||||.:.|::||.||:.:     ..|..||.|.....
Zfish   311 RIIGGVEAALGRWPWQVSLYYNNRHICGGSIITNQWIVTAAHCVHNYRLPQVPSWVVYAGIITSN 375

  Fly    99 NAQFTHWVG----------NGNFIKHSSADIALIRI-PHVDFWHMVNKVELPSYNDRYNDYNEWW 152
            .|:...:.|          |.|...|.: ||||::: ..::|...:..|.||.|:.......:.|
Zfish   376 LAKLAQYQGFAVERIIYNKNYNHRTHDN-DIALVKLKTPLNFSDTIRPVCLPQYDHDLPGGTQCW 439

  Fly   153 AVACGWGGTY-DGSPLPDYLQCVDLQIIHNSECSG---YYGSVGDNILCVRTPDGK-STCGGDSG 212
              ..|||.|. |...:|:.|:...:.:|...:|:.   |.|.:...:||....:|| ..|.||||
Zfish   440 --ISGWGYTQPDDVLIPEVLKEAPVPLISTKKCNSSCMYNGEITSRMLCAGYSEGKVDACQGDSG 502

  Fly   213 GPLVTHDGT--KLVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWIRD 255
            ||||..|..  :||||.::|:  || :...|..:.:|...|.||.|
Zfish   503 GPLVCQDENVWRLVGVVSWGT--GCAEPNHPGVYSKVAEFLGWIYD 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	73/237 (31%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	75/240 (31%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	73/237 (31%)
		Tryp_SPc	312..547	CDD:238113	75/240 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910