DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and tmprss13b

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_005165399.1	Gene:	tmprss13b / 564693	ZFINID:	ZDB-GENE-090309-2	Length:	475	Species:	Danio rerio

Alignment Length:	243	Identity:	75/243 - (30%)
Similarity:	109/243 - (44%)	Gaps:	35/243 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDADSVT-------VYFG 93
            :..||..|..|.||..|:...|.|.|...||||::|.|:::||.||.....|.:       ||.|
Zfish   234 VSSRIIGGSVAAEGHWPWQASLHFQGKHSCGGSLVAPDFIITAAHCFPKETSGSQLPSNWKVYIG 298

  Fly    94 ATWRTNAQFTHWVGNGNFIKH-------SSADIALIRI--PHVDFWHMVNKVELPSYNDRYNDYN 149
            ...:......::|  ...|.|       .:.||||:::  |..|    |..:.||.....:....
Zfish   299 FVSQLKLPSPYYV--KEIILHEKYNPTTKNYDIALLKLNKPASD----VEPICLPVIGQTFPPAK 357

  Fly   150 EWWAVACGWGGTYDGS-PLPDYLQCVDLQIIHNSECSG---YYGSVGDNILCV-RTPDGKSTCGG 209
            :.|..  |:|....|| .:...|..|.:.:|.:|.|:.   |.|.:.:|:.|. ....||.:|.|
Zfish   358 QCWTT--GFGVIRQGSNSVSTSLMEVTVSLIDSSVCNSPNVYNGEITENMQCAGDLRGGKDSCQG 420

  Fly   210 DSGGPLV--THDGT-KLVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWI 253
            ||||||.  ::||. .|.|||::|.  || |...|..:..|..:|.||
Zfish   421 DSGGPLACKSNDGQWFLTGVTSWGE--GCGQVNRPGVYSDVAKYLMWI 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	73/238 (31%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	74/239 (31%)
tmprss13b	XP_005165399.1	SRCR_2	147..230	CDD:295335
		Tryp_SPc	237..466	CDD:214473	73/238 (31%)
		Tryp_SPc	238..469	CDD:238113	74/239 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910