DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and prss60.2

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	240	Identity:	83/240 - (34%)
Similarity:	113/240 - (47%)	Gaps:	27/240 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MQGRITNGYPAEEGKAPYTVGLGFS--GGWWCGGSIIAHDWVLTAEHCIG--DADSVTVYFGATW 96
            :..||..|..|.||..|:.|.|...  ||.:||||:|:.:|||||.||:.  ...|:.||.|...
Zfish    30 LNSRIVGGVNAPEGSWPWQVSLQSPRYGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLGRRT 94

  Fly    97 RTNAQFTHWVGN--GNFIKHSS-------ADIALIRIPH-VDFWHMVNKVELPSYNDRYNDYNEW 151
            :.... ||....  ...|.|||       .||||:|:.. |.|...:..|.|.:.|..|:.....
Zfish    95 QQGVN-THETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSS 158

  Fly   152 WAVACGWGGTYDG--SPLPDYLQCVDLQIIHNSECSGYYGS--VGDNILCV-RTPDGKSTCGGDS 211
            |..  |||....|  .|.|..||...:.::.|..|:...||  |.:|::|. ....||.||.|||
Zfish   159 WIT--GWGDVQAGVNLPAPGILQETMIPVVANDRCNAQLGSGTVTNNMICAGLAKGGKDTCQGDS 221

  Fly   212 GGPLVTHDGTKLV--GVTNFGSVAGC-QSGAPAGFQRVTYHLDWI 253
            |||:||...|..:  |:|::|  .|| ...:|..:.||:.:..||
Zfish   222 GGPMVTRLCTVWIQAGITSWG--YGCADPNSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	81/235 (34%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	82/236 (35%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	81/235 (34%)
		Tryp_SPc	34..267	CDD:238113	82/236 (35%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910