DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and C1s1

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001091086.1	Gene:	C1s1 / 50908	MGIID:	1355312	Length:	694	Species:	Mus musculus

Alignment Length:	288	Identity:	68/288 - (23%)
Similarity:	100/288 - (34%)	Gaps:	78/288 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GATMPRLATEKLTPVHTKDMQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHC 81
            |..:||.......|.....:..||..|.||:....|:.|   |.......|::|...|||||.|.
Mouse   421 GIELPRCIPACGVPTEPFQVHQRIFGGQPAKIENFPWQV---FFNHPRASGALINEYWVLTAAHV 482

  Fly    82 IGDADSVTVYFG-----ATWRTNAQ-------FTH--W--VGNGNFIKHSSADIALIRIPH-VDF 129
            :.......:|.|     .|...|||       |.|  |  ..:.|...:...||||:::.. |..
Mouse   483 LEKISDPLMYVGTMSVRTTLLENAQRLYSKRVFIHPSWKKEDDPNTRTNFDNDIALVQLKDPVKM 547

  Fly   130 WHMVNKVELPSYNDRYNDYNEWWAVACGWGGT--------YDGSPLP------------------ 168
            ...|:.:.||..:..||.......:..|||.|        ..|:.:|
Mouse   548 GPKVSPICLPGTSSEYNVSPGDMGLISGWGSTEKKVFVINLRGAKVPVTSLETCKQVKEENPTVR 612

  Fly   169 --DYLQCVDLQIIHNSECSGYYGSVGDNILCVRTPDGKSTCGGDSGG------PLVTHDGTKLVG 225
              ||:                   ..||::|. ...|..:|.|||||      |.||.....:.|
Mouse   613 PEDYV-------------------FTDNMICA-GEKGVDSCHGDSGGAFAFQVPNVTVPKFYVAG 657

  Fly   226 VTNFGSVAGCQSGAPAGFQRVTYHLDWI 253
            :.::|.    :.|....:.:|..::|||
Mouse   658 LVSWGK----RCGTYGVYTKVKNYVDWI 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	62/264 (23%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	63/265 (24%)
C1s1	NP_001091086.1	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:373209
		CUB	181..293	CDD:366096
		CCP	307..361	CDD:153056
		CCP	365..428	CDD:153056	3/6 (50%)
		Tryp_SPc	443..681	CDD:214473	62/264 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000