DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and Tmprss9

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	249	Identity:	72/249 - (28%)
Similarity:	110/249 - (44%)	Gaps:	37/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 GRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDADSVTVYFGATWRTNAQF 102
            |||..|..|..|:.|:.|.|..:...:||.:||...|:::|.||..:...     .|.|...|..
Mouse   454 GRIVGGVEAAPGEFPWQVSLRENHEHFCGATIIGARWLVSAAHCFNEFQD-----PAQWAAQAGS 513

  Fly   103 THWVGNG---------NFIKH-------SSADIALIRIPH-VDFWHMVNKVELPSYNDRYNDYNE 150
            .|..|:.         ...||       :..|:|::.:.. :.|...|....||:....:....:
Mouse   514 VHLSGSEASAVRTRVLRIAKHPAYDADTADFDVAVLELARPLPFGRYVQPACLPAATHVFPPGKK 578

  Fly   151 WWAVACGWGGTY---DGSPLPDYLQCVDLQIIHNSECSGYYG-SVGDNILCVRTPDGK-STCGGD 210
              .:..|||  |   |....|:.||...::::..|.||..|| |:.|.::|....||| .:|.||
Mouse   579 --CLISGWG--YLKEDFLVKPEVLQKATVELLDQSLCSSLYGHSLTDRMVCAGYLDGKVDSCQGD 639

  Fly   211 SGGPLVTHDGTK---LVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWIRDHTGIA 260
            ||||||..:.:.   |.|:.::|  .|| ::..|..:.|||...|||.:.|..|
Mouse   640 SGGPLVCEEPSGRFFLAGIVSWG--IGCAEARRPGVYTRVTRLRDWILEVTSAA 691

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	67/239 (28%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	68/241 (28%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473	67/239 (28%)
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910