DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and TMPRSS11F

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_997290.2	Gene:	TMPRSS11F / 389208	HGNCID:	29994	Length:	438	Species:	Homo sapiens

Alignment Length:	295	Identity:	80/295 - (27%)
Similarity:	122/295 - (41%)	Gaps:	87/295 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KLTPVHTKDM-----------------------------QGRITNGYPAEEGKAPYTVGLGFSG- 61
            :|||:.:|.|                             |||.|    |.||:.|:...|...|
Human   169 RLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRET----AMEGEWPWQASLQLIGS 229

  Fly    62 GWWCGGSIIAHDWVLTAEHCIGDADSVTVYFGATWRTNAQFTHWVG------------------- 107
            |..||.|:|::.|:|||.||.             |: |...|.|:.
Human   230 GHQCGASLISNTWLLTAAHCF-------------WK-NKDPTQWIATFGATITPPAVKRNVRKII 280

  Fly   108 -NGNFIKHSSA-DIALIRI-PHVDFWHMVNKVELPSYNDRYNDYNEWWAVACGWGGTYDGSPLPD 169
             :.|:.:.::. ||||::: ..|:|.::|.:|.||..:.:......  ....|:|...|..|:.:
Human   281 LHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTS--VFVTGFGSIVDDGPIQN 343

  Fly   170 YLQCVDLQIIHNSECSG---YYGSVGDNILCVRTPDGK-STCGGDSGGPLV--THDGTKLVGVTN 228
            .|:...::.|....|:.   |.|.:...:||....:|| ..|.||||||||  .||...:||:.:
Human   344 TLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVS 408

  Fly   229 FGSVAGCQSGA----PAGFQRVTYHLDWIRDHTGI 259
            :|     ||.|    |..:.|||.:.|||...||:
Human   409 WG-----QSCALPKKPGVYTRVTKYRDWIASKTGM 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	69/246 (28%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	70/248 (28%)
TMPRSS11F	NP_997290.2	SEA	59..154	CDD:279699
		Tryp_SPc	205..432	CDD:214473	71/251 (28%)
		Tryp_SPc	206..435	CDD:238113	73/253 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910